显微镜下精索静脉结扎术联合电生理治疗精索静脉曲张所致弱精子症的效果观察  

Effect of microscopic ligation of spermatic vein combined with electrophysiology in the treatment of asthenospermia caused by varicocele

作　　者：李金永[1] 王淑娟 闻玉钢 王志强[1] LI Jinyong;WANG Shujuan;WEN Yugang;WANG Zhiqiang(Department of Urology,the First Hospital of Yinchuan,Yinchuan 750001,China)

机构地区：[1]宁夏银川市第一人民医院泌尿外科,宁夏银川750001

出　　处：《宁夏医学杂志》2024年第11期983-986,共4页Ningxia Medical Journal

摘　　要：目的 观察显微镜下精索静脉结扎术联合电生理治疗精索静脉曲张所致弱精子症的效果。方法 回顾性分析57例精索静脉曲张所致弱精子症患者的临床资料,根据治疗方法不同将其分成观察组(n=29)与对照组(n=28)。对照组采用显微镜下精索静脉结扎术治疗,观察组采用显微镜下精索静脉结扎术联合电生理治疗。对比2组患者的临床疗效、精液质量、生殖激素、精浆丙二醛(MDA)、超氧化物歧化酶(SOD)水平及配偶的妊娠率。结果 观察组总有效率为89.66%,对照组为67.86%(P<0.05)。2组患者治疗后a级精子、精子活率、精子密度与a+b级精子均升高(P<0.05);2组患者卵泡刺激素(FSH)、黄体生成素(LH)均降低(P<0.05);2组患者抑制素B、总睾酮(TT)均升高(P<0.05);2组患者精浆SOD水平均升高(P<0.05);2组精浆MDA水平均降低(P<0.05)。结论 精索静脉曲张所致弱精子症采用显微镜下精索静脉结扎术联合电生理治疗疗效显著,可提升精液质量,调节生殖激素,减轻精子氧化应激损伤,提升配偶妊娠率。Objective To observe the effect of microscopic ligation of spermatic vein combined with electrophysiology in the treatment of asthenospermia caused by varicocele.Methods A retrospective analysis was conducted on the clinical data of 57 patients with oligozoospermia caused by varicocele.They were divided into an observation group(n=29)and a control group(n=28).The patients in the control group received the treatment of microscopic varicocelectomy,and the patients in the observation group was treated with microscopic ligation of spermatic vein combined with electrophysiology.The clinical efficacy,semen quality,reproductive hormones,the levels of malondialdehyde(MDA)and superoxide dismutase(SOD)in seminal plasma and the spouse pregnancy rate were compared in the two groups.Results The total effective rate of the observation group(89.66%)was higher than that in the control group(67.86%,P<0.05).After treatment,the a-grade sperm,sperm motility,sperm density and a+b-grade sperm in the two groups increased(P<0.05).Follicle stimulating hormone(FSH)and luteinizing hormone(LH)decreased in the two groups(P<0.05).Inhibin B and total testosterone(TT)in the two groups increased(P<0.05).The serum level of SOD in the two groups increased(P<0.05).The levels of MDA decreased in both groups(P<0.05).Conclusion The microscopic ligation of spermatic vein combined with electrophysiology has significant therapeutic effects on the asthenospermia caused by varicocele,which can improve semen quality,regulate reproductive hormones,reduce oxidative stress damage of sperm,and increase the pregnancy rate of spouses.

关 键 词：电生理 弱精子症 显微镜下精索静脉结扎术 临床疗效 精索静脉曲张 

分 类 号：R699.8[医药卫生—泌尿科学]