Influence of anodization conditions on deposition of hydroxyapatite on α/β Ti alloys for osseointegration:Atomic force microscopy analysis  

阳极氧化条件对骨整合用α/β钛合金表面沉积羟基磷灰石的影响:原子力显微镜分析

作　　者：Rania E.HAMMAM Engie M.SAFWAT Soha A.ABDEL-GAWAD Madiha SHOEIB Shimaa EL-HADAD 

机构地区：[1]Faculty of Engineering,Modern University for Technology and Information(MTI),Cairo 11585,Egypt [2]Restorative and Dental Materials Department,National Research Centre,Giza 12622,Egypt [3]Chemistry Department,Faculty of Science,Cairo University,Giza 12613,Egypt [4]Central Metallurgical Research and Development Institute,CMRDI,P.O.87,Helwan 11421,Egypt

出　　处：《Transactions of Nonferrous Metals Society of China》2024年第11期3629-3649,共21页中国有色金属学报（英文版）

基　　金：financial support from the Science and Technology Development Fund of Egypt (No.5540)。

摘　　要：Integrating titanium-based implants with the surrounding bone tissue remains challenging.This study aims to explore the impact of different anodization voltages(20−80 V)on the surface topography of two-phase(α/β)Ti alloys and to produce TiO_(2) films with enhanced bone formation abilities.Scanning electron microscopy coupled with energy dispersive spectroscopy(SEM−EDS)and atomic force microscopy(AFM)were applied to investigate the morphological,chemical,and surface topography of the prepared alloys and to confirm the growth of hydroxyapatite(HA)on their surfaces.Results disclosed that the surface roughness of TiO_(2) films formed on Ti−6Al−7Nb alloys was superior to that of Ti−6Al−4V alloys.Ti−6Al−7Nb alloy anodized at 80 V had the highest yields of HA after immersion in simulated body fluid with enhanced HA surface coverage.The developed HA layer had a mean thickness of(128.38±18.13)μm,suggesting its potential use as an orthopedic implantable material due to its promising bone integration and,hence,remarkable stability inside the human body.将钛基植入物与周围骨组织整合仍然具有挑战性。本研究旨在探讨不同阳极氧化电压(20~80 V)对双相(α/β)钛合金表面形貌的影响,并制备具有增强成骨能力的TiO_(2)薄膜。采用扫描电子显微镜结合能量色散光谱(SEM-EDS)和原子力显微镜(AFM)研究合金的显微组织、化学成分和表面形貌,并确认其表面羟基磷灰石(HA)的生长。结果表明,与Ti-6Al-4V合金相比,Ti-6Al-7Nb合金表面形成的TiO_(2)薄膜具有更优的粗糙度。在模拟体液中浸泡后,经80 V阳极处理的Ti-6Al-7Nb合金表面HA覆盖率提高,沉积的HA最多,其平均厚度为(128.38±18.13)μm。结果表明经阳极氧化处理的钛合金具有良好的骨整合性及在人体内的稳定性,具有作为骨科植入材料的潜力。

关 键 词：material science electrochemical anodization process atomic force microscopy α/βTi alloys hydroxyapatite deposition 

分 类 号：TG174.4[金属学及工艺—金属表面处理] R318.08[金属学及工艺—金属学]