基于中医“从肝治痰”论治慢性阻塞性肺疾病气道黏液高分泌  

Treating airway mucus hypersecretion in chronic obstructive pulmonary disease based on treating phlegm from liver in TCM

作　　者：龚钤升 刘炜 GONG Qiansheng

机构地区：[1]贵州中医药大学,贵州贵阳550025 [2]贵州中医药大学第二附属医院,贵州贵阳550003

出　　处：《中医临床研究》2024年第29期135-139,共5页Clinical Journal Of Chinese Medicine

基　　金：国家自然科学基金委员会资助项目计划书地区科学基金项目(81760774);贵州省中医药管理局中医药、民族医药科学技术研究项目(QZYY-2021-124);贵州中医药大学校内课题(2019)。

摘　　要：慢性阻塞性肺疾病(简称慢阻肺)是常见的慢性呼吸系统疾病,该病日久难愈,严重威胁人类健康。气道黏液高分泌是慢阻肺重要的病理特征,也是导致慢阻肺急性加重和病情进展的重要因素。慢阻肺可归属于中医肺胀的范畴,痰作为肺胀的重要致病因素,不仅与肺、脾、肾功能失调有关,还与肝的病理状态存在密切的联系,故探讨肝与痰在慢阻肺发生发展中的作用颇为重要。慢阻肺气道黏液高分泌与肺胀中“宿痰伏肺”相契合。中医在治疗肺胀方面多从痰论治,肝对气机的宣畅升降作用在治疗痰的过程中起到积极的作用,故研究基于“从肝治痰”理论对慢阻肺气道黏液高分泌进行证治探讨,以期为中医药治疗该疾病提供思路和临床诊疗方法,提高中医药治疗肺胀的临床疗效。Chronic obstructive pulmonary disease(COPD)is a common chronic respiratory disease.This disease has a long course of disease,is difficult to cure,and seriously threatens human health.Airway mucus hypersecretion is an important pathological feature of COPD and an important factor leading to acute exacerbation and progression of COPD.COPD belongs to the category of lung distension in traditional Chinese medicine.As an important pathogenic factor of lung distension,phlegm is not only related to the dysfunction of lung,spleen and kidney,but also closely related to the pathological state of liver,so it is very important to explore the role of liver and phlegm in the occurrence and development of COPD.Airway mucus hypersecretion in COPD is consistent with the‘accumulated phlegm in the lungs’of lung distension.In terms of the treatment of lung distention,TCM method is mainly based on Clinical Journal of Chinese Medicine 2024-136-Vol.(16)No.29 the theory of treating phlegm from the liver,and the function of the liver in the promotion and elevation of Qi(气)plays an active role in the treatment of phlegm.Therefore,based on the theory of treating phlegm from the liver,this paper discusses the syndrome differentiation and treatment of airway mucus hypersecretion in COPD,providing ideas and clinical diagnosis and treatment methods for the treatment of airway mucus hypersecretion in COPD in TCM,so as to improve the clinical efficacy of TCM in the treatment of lung distention.

关 键 词：慢性阻塞性肺疾病 痰 气道黏液高分泌 肝 

分 类 号：R256.1[医药卫生—中医内科学]