皮肤微生态与皮肤老化关系的研究进展  

Advances in Research on the Relationship between Skin Microbiota and Skin Aging

作　　者：史敏[1] 程薇薇 毕芳芳 张露(综述)[1] 丁欣强(审校)[2] SHI Min;CHENG Weiwei;BI Fangfang;ZHANG Lu;DING Xinqiang(Xi’an Peihua University,Xi’an 710125,Shaanxi,China;Department of Dermatology,Xi'an Children’s Hospital,Xi’an 710003,Shaanxi,China)

机构地区：[1]西安培华学院,陕西西安710125 [2]西安市儿童医院皮肤科,陕西西安710003

出　　处：《中国美容医学》2024年第12期189-192,共4页Chinese Journal of Aesthetic Medicine

基　　金：陕西省自然科学基础研究计划面上项目(编号:2022JM-558);西安培华学院校级科研项目(编号:PHKT2306)。

摘　　要：皮肤是人体最大的体表器官,其结构从浅至深依次为表皮层、真皮层和皮下组织。皮肤表面及腺体等部位定植了众多微生物菌落,统称为皮肤微生态。皮肤微生态在皮肤的健康和内稳态方面发挥着关键作用,与皮肤衰老存在着密切关系。本文在回顾皮肤组织结构与功能的基础上,对皮肤微生态及其与皮肤衰老关系的临床研究进展进行了总结,探讨了目前皮肤微生态与皮肤衰老研究和临床应用中存在的问题,以期为未来皮肤抗衰老的临床研究和皮肤微生态产品的开发提供参考。The skin is the largest surface organ of the human body,with its structure consisting of the epidermis,dermis,and subcutaneous tissue from superficial to internal.Numerous microbial colonies are colonized on the surface of the skin and glands,was known as the skin microbiota.The skin microbiota plays a crucial role in skin health and homeostasis,and is closely related to skin aging.We have summarized the composition and role of skin microbiota,the relationship between skin microbiota and skin aging,and the application of delaying skin aging through microbiota regulation,and analyzed and explored the current research and clinical applications issues of skin microbiota and skin aging,in order to provide reference for clinical research on skin anti-aging and the development of skin microbiota products.

关 键 词：皮肤微生态 衰老 皮肤老化 微生态治疗 

分 类 号：R322.99[医药卫生—人体解剖和组织胚胎学]