二硫化钼在光动力疗法和光热疗法中的应用  

Applications of molybdenum disulfide in photodynamic therapy and photothermal therapy

作　　者：廖师琴[1] 王清清 Liao Shiqin;Wang Qingqing(Jiangxi Center for Modern Apparel Engineering and Technology,Jiangxi Institute of Fashion Technology,Nanchang 330201)

机构地区：[1]江西服装学院江西省现代服装工程技术研究中心,南昌330201

出　　处：《化工新型材料》2024年第12期263-269,共7页New Chemical Materials

基　　金：江西省教育厅科学技术研究项目(GJJ212406和GJJ202405)。

摘　　要：综述了MoS_(2)在光动力疗法(PDT)和光热疗法(PTT)中的抗菌应用进展。MoS_(2)凭借其独特的层状结构和高活性位点,成为光驱动抗菌领域的高潜力材料。讨论了PDT与PTT的基本原理及其协同抗菌机制,分析了MoS_(2)的结构特性,展示了MoS_(2)在增强抗菌效果上的优势,并详细阐述了其在PDT、PTT及协同抗菌中的具体应用。然而,当前应用仍面临氧化降解、易聚集、靶向效率低及生物安全性等挑战。未来,需进一步优化MoS_(2)性能,加强安全性评估,以推动其在光驱动抗菌领域的广泛应用。This review summarized the progress in the antibacterial applications of molybdenum disulfide(MoS_(2))in photodynamic therapy(PDT)and photothermal therapy(PTT).With its unique layered structure and high active sites,MoS_(2) emerges as a high-potential material in the field of light-driven antibacterial therapy.The paper discussed the fundamental principles of PDT and PTT as well as their synergistic antibacterial mechanisms.The structural properties of MoS_(2) were analyzed,highlighting its advantages in enhancing antibacterial efficacy.Furthermore,specific applications of MoS_(2) in PDT,PTT,and their synergistic antibacterial strategies were elaborated.However,current applications still face challenges such as oxidative degradation,easy aggregation,low targeting efficiency,and biosafety concerns.Future research should focus on optimizing the properties of MoS_(2),strengthening safety assessments,and promoting its widespread application in light-driven antibacterial therapy.

关 键 词：二硫化钼 光动力疗法 光热疗法 抗菌 协同抗菌 

分 类 号：TQ13[化学工程—无机化工] R318[医药卫生—生物医学工程]