分析双氯芬酸、萘丁美酮治疗骨关节炎的效果  

Analysis of the Efficacy of Diclofenac and Nabumetone in the Treatment of Osteoarthritis

作　　者：刘春兰 路俊华 LIU Chunlan;LU Junhua(Department of Pharmacy,Zibo Hospital of Traditional Chinese Medicine,Zibo 255000,Shandong,China)

机构地区：[1]淄博市中医医院药学部,山东淄博255000

出　　处：《系统医学》2024年第21期184-186,共3页Systems Medicine

摘　　要：目的评析骨关节炎患者运用双氯芬酸、萘丁美酮治疗的效果。方法非随机选取2022年6月—2023年6月淄博市中医医院接诊的66例骨关节炎患者为研究对象,根据治疗方法不同分为对照组(33例,双氯芬酸治疗)和观察组(33例,萘丁美酮治疗)。对比两组治疗总有效率、不良反应发生率、膝关节功能评分。结果两组治疗总有效率对比,差异无统计学意义(P>0.05)。观察组不良反应发生率为6.06%(2/33),低于对照组的27.27%(9/33),差异有统计学意义(χ^(2)=5.345,P<0.05)。两组治疗后膝关节功能评分对比,差异无统计学意义(P均>0.05)。结论骨关节炎患者运用双氯芬酸和萘丁美酮均可以获得显著的效果,但是萘丁美酮的治疗安全性更高。Objective To evaluate the effect of diclofenac and naftobumethone in the treatment of osteoarthritis.Methods A total of sixty-six patients with osteoarthritis admitted to Zibo Hospital of Traditional Chinese Medicine from June 2022 to June 2023 were non-randomly selected as the research objects.According to different treatment methods,they were divided into the control group(thirty-three cases,diclofenac treatment)and the observation group(thirty-three cases,naproxen treatment).The total effective rate,incidence of adverse reactions and knee function score were compared between the two groups.Results There was no statistically significant difference in the total effective rate between the two groups(P>0.05).The incidence of adverse reactions in the observation group was 6.06%(2/33),which was lower than 27.27%(9/33)in the control group,the difference was statistically significant(χ2=5.345,P<0.05).There was no statistically statistically significant difference in knee function scores between the two groups after treatment(all P>0.05).Conclusion Diclofenac and nbumedone can achieve significant results in patients with osteoarthritis,but nbumedone has a higher therapeutic safety.

关 键 词：骨关节炎 双氯芬酸 萘丁美酮 疗效 膝关节功能 

分 类 号：R4[医药卫生—临床医学]