基于属性层次模型的伊伐布雷定药物利用评价标准的建立与应用  

Establishment and Application of Evaluation Criteria for Drug Utilization Evaluation of Ivabradine Based on Attribute Hierarchy Model

作　　者：王栓 齐腊梅[1] 黄灿[1] WANG Shuan;QI Lamei;HUANG Can(Dept.of Pharmaceutical Administration,Anqing Municipal Hospital,Anhui Anqing 246000,China)

机构地区：[1]安庆市立医院药事管理科,安徽安庆246000

出　　处：《中国医院用药评价与分析》2024年第11期1376-1380,共5页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：中华国际医学交流基金会临床药学专项基金项目(No.Z-2021-46-2101)。

摘　　要：目的:建立伊伐布雷定药物利用评价(DUE)标准,采用属性层次模型(AHM)法综合评价伊伐布雷定临床应用的合理性。方法:以伊伐布雷定的药品说明书、相关指南或专家共识为依据,建立伊伐布雷定DUE标准,采用AHM法评价2022年5月至2024年4月该院83份应用伊伐布雷定的归档病历。结果:伊伐布雷定不合理使用率由高至低排序居前3位的分别为给药方式不合理(60例,占72.29%)、遴选药品不合理(41例,占49.40%)、用法与用量不合理(29例,占34.94%)。83份病历中,病历得分(MRS)≥90分的有14份(占16.87%),MRS为70~<90分的有39份(占46.99%),MRS为60~<70分的有23份(占27.71%),MRS<60分的有7份(占8.43%)。结论:该院伊伐布雷定的临床应用中存在较多不合理用药情况,基于AHM法的DUE评价标准,能直观地量化评价结果。OBJECTIVE:To establish the drug utilization evaluation(DUE)criteria of ivabradine,and evaluate the rationality of clinical application of ivabradine by attribute hierarchy model(AHM).METHODS:Based on drug instructions of ivabradine,related guidelines or expert consensus,the DUE criteria of ivabradine was established,and the archived medical records of 83 cases with ivabradine application in the hospital from May 2022 to Apr.2024 were evaluated by AHM method.RESULTS:The top 3 irrational rates of ivabradine from high to low were improper administration routes in 60 cases(72.29%),improper selection of drugs in 41 cases(49.40%),improper usage and dosage in 29 cases(34.94%).Among the 83 medical records,14 cases(16.87%)had medical record score(MRS)≥90 points,39 cases(46.99%)had MRS from 70 to<90 points,23 cases(27.71%)had MRS from 60 to<70,and 7 cases(8.43%)had MRS<60 points.CONCLUSIONS:There are many irrational application of ivabradine in clinical application in the hospital,DUE criteria based on AHM method can intuitively quantify the evaluation results.

关 键 词：伊伐布雷定 药物利用评价 属性层次模型 评价标准 

分 类 号：R972[医药卫生—药品]