干姜化学成分和药理作用研究进展  

Research Progress on Chemical Constituents and Pharmacological Effects of Dried Ginger

作　　者：吴萍 蒯梦妮 李乐 张志国 周逸群[2,5,6] Wu Ping;Kuai Mengni;Li Le;Zhang Zhiguo;Zhou Yiqun(Changde Hospital,Xiangya School of Medicine,Central South University(The First People's Hospital of Changde City),Changde 415000,China;National Traditional Chinese Medicine Inheritance Studio of Famous Expert Zhang Zhiguo,Changsha 410007,China;The Hospital Affiliated to Southwest Medical University,Luzhou 646000,China;The First Hospital Affiliated to Hunan University of Chinese Medicine,Changsha 410007,China;College of Pharmacy,Hunan University of Chinese Medicine,Changsha 410208,China;Hunan Key Laboratory of Druggability and Preparation Modification for Traditional Chinese Medicine,Changsha 410208,China)

机构地区：[1]中南大学湘雅医学院附属常德医院(常德市第一人民医院),湖南常德415000 [2]张志国全国名老中医药专家传承工作室,湖南长沙410007 [3]西南医科大学附属医院,四川泸州646000 [4]湖南中医药大学第一附属医院,湖南长沙410007 [5]湖南中医药大学药学院,湖南长沙410208 [6]中药成药性与制剂制备湖南省重点实验室,湖南长沙410208

出　　处：《亚太传统医药》2024年第11期242-246,共5页Asia-Pacific Traditional Medicine

基　　金：湖南省中医药管理局项目(B2023136);长沙市自然科学基金项目(kq2208194);湖南省自然科学基金项目(2023JJ50445);2024年度创建“中国长寿之乡”研究专项课题。

摘　　要：中药干姜为姜科植物姜(Zingiber officinale Rosc.)的干燥根茎。性辛、热,归脾、胃、肾、心、肺经,具有温中散寒、回阳通脉、温肺化饮的功效,用于脘腹冷痛、呕吐泄泻、肢冷脉微、寒饮喘咳等症。对干姜的化学成分及药理研究进行综述,干姜化学成分主要为挥发油类、姜辣素类、二苯庚烯烷类,其药理作用主要为抗炎、抗氧化、抗菌、抗癌等。目前干姜的化学成分多集中在挥发油与姜辣素类成分的研究,虽然对其药理作用进行了大量的研究,但大部分药效作用机制尚不明确,还有待进一步研究。Zingiberris Rhizoma is the dried rhizomes of Zingiber officinale Rosc.It is pungent and hot,and belongs to the spleen,stomach,kidney,heart and lung meridians.Zingiberris Rhizoma has the effects of warming the middle and dispersing cold,restoring yang and dredging meridians,warming lung and resolving fluid retention.It is used for abdominal cold pain,vomiting and diarrhea,cold pulse of limbs,cold fluid retention,cough and asthma.The chemical constituents and pharmacological studies of Zingiberris Rhizoma were reviewed.It's found that the main chemical constituents of Zingiberris Rhizoma were volatile oils,gingerols and diphenylheptanes.It's pharmacological effects were mainly anti-inflammatory,anti-oxidation,anti-bacterial and anti-cancer.At present,the chemical components of Zingiberris Rhizoma are mostly concentrated in the study of volatile oil and gingerols.Although researchers have done a lot of research on the pharmacological effects of Zingiberris Rhizoma,most of the pharmacodynamic mechanisms are still unclear and need to be further studied.

关 键 词：干姜 化学成分 药理作用 抗癌 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]