Mirids secrete a TOPLESS targeting protein to enhance JA-mediated defense and gossypol accumulation for antagonizing cotton bollworms on cotton plants  

作　　者：Yu-Pei Mu Dian-Yang Chen Yu-Jie Liu Ming-Yu Zhu Xian Zhang Yin Tang Jia-Ling Lin Mu-Yang Wang Xiao-Xia Shangguan Xiao-Ya Chen Chengshu Wang Ying-Bo Mao 

机构地区：[1]CAS Key Laboratory of Insect Developmental and Evolutionary Biology,CAS Center for Excellence in Molecular Plant Sciences,Shanghai Institute of Plant Physiology and Ecology,University of CAS,Chinese Academy of Sciences,Shanghai 200032,China [2]National Key Laboratory of Plant Molecular Genetics,CAS Center for Excellence in Molecular Plant Sciences,Shanghai Institute of Plant Physiology and Ecology,University of CAS,Chinese Academy of Sciences,Shanghai 200032,China [3]Institute of Cotton Research,Shanxi Agricultural University,Yuncheng 044000,China

出　　处：《Molecular Plant》2024年第11期1687-1701,共15页分子植物（英文版）

基　　金：supported by Biological Breeding-Major Projects(2023ZD04070);the National Natural Science Foundation of China(32072430 and 32000221);the Science and Technology Commission of Shanghai Municipality(22ZR1469300 and 21ZR1471000).

摘　　要：Most coexisting insect species exhibit stunted growth compared to individual species on plants.This phenomenon reflects an interspecific antagonism drawing extensive attention,while the underlying mechanisms remain largely uncharacterized.Mirids(Apolygus lucorum)and cotton bollworms(Helicoverpa armigera)are two common cotton pests.We identified a secretory protein,ASP1,from the oral secretion of mirids,found in the nucleus of mirid-infested cotton leaves.ASP1 specifically targets the transcriptional co-repressor TOPLESS(TPL)and inhibits NINJA-mediated recruitment of TPL,promoting plant defense response and gossypol accumulation in cotton glands.ASP1-enhanced defense inhibits the growth of cotton bollworms on cotton plants,while having limited impact on mirids.The mesophyll-feeding characteristic allows mirids to avoid most cotton glands,invalidating cotton defense.Our investigation reveals the molecular mechanism by which mirids employ cotton defense to selectively inhibit the feeding of cotton bollworms.

关 键 词：oral secretion plant defense co-repressor TOPLESS MIRIDS Apolygus lucorum cotton bollworms Helicoverpa armigera 

分 类 号：Q94[生物学—植物学]