肠内营养支持对早期急性失代偿性心力衰竭患者的心功能及预后的影响  

Effect of Enteral Nutrition Support on Cardiac Function and Prognosis in Patients with Early Acute Decompensated Heart Failure

作　　者：靳婷 宋彦霞 JIN Ting;SONG Yanxia(Department of Gastroenterology,People's Hospital of Tongchuan,Tongchuan Shaanxi 727000)

机构地区：[1]铜川市人民医院消化内科,陕西铜川727000 [2]西安石油大学医院内科,陕西西安710065

出　　处：《医学临床研究》2024年第11期1733-1735,1739,共4页Journal of Clinical Research

摘　　要：【目的】探讨肠内营养治疗对早期急性失代偿性心力衰竭患者的心功能及预后的影响。【方法】回顾性分析2019年1月至2021年1月两院收治的100例早期急性失代偿性心力衰竭患者的临床资料,根据临床治疗方法的不同将其分为观察组和对照组,每组50例。对照组采用常规抗心衰的治疗,观察组在对照组的基础上给予肠内营养支持。比较两组患者的心功能指标、营养状态指标及患者出院后1年内的随访结果。【结果】治疗后,两组患者左心室舒张末期内径、左心室收缩末期内径及血清脑利钠肽水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组左心室射血分数均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。治疗后,两组患者血清白蛋白、转铁蛋白、前白蛋白、血红蛋白均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组患者出院后随访1年内心力衰竭复发率、病死率及疾病恶化率均明显低于对照组,差异有统计学意义(P<0.05)。【结论】肠内营养支持可改善早期急性失代偿性心力衰竭患者心功能和营养状态及预后,值得临床应用。【Objective】To investigate the effect of enteral nutrition on cardiac function and prognosis of patients with early acute decompensated heart failure.【Methods】The clinical data of 100 patients with early acute decompensated heart failure admitted to our hospital from January 2019 to January 2021 were retrospectively analyzed,and they were divided into the observation group and the control group according to different treatment methods,with 50 cases in each group.The control group received conventional anti-heart failure treatment,and the observation group was given enteral nutrition support on the basis of the control group.The changes of cardiac function indexes,nutritional status indexes and follow-up results within 1 year after discharge were compared between the two groups.【Results】After treatment,left ventricular end-diastolic diameter,left ventricular end-systolic diameter and serum brain natriuretic peptide levels in 2 groups were lower than before treatment,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).Left ventricular ejection fraction in both groups was higher than before treatment,and the observation group was higher than the control group,the difference was statistically significant(P<0.05).After treatment,serum albumin,transferrin,prealbumin and hemoglobin in 2 groups were higher than before treatment,and the observer group was higher than the control group,the difference was statistically significant(P<0.05).The recurrence rate of heart failure,mortality rate and disease deterioration rate of patients in the observation group were significantly lower than those in the control group within 1 year after discharge,with statistical significance(P<0.05).【Conclusion】Enteral nutrition support can improve the cardiac function,nutritional status and prognosis of patients with early acute decompensated heart failure,and is worthy of clinical application.

关 键 词：心力衰竭/治疗 急性病 肠道营养 营养支持 心脏功能试验 预后 

分 类 号：R541.61[医药卫生—心血管疾病]