早期母乳联合母乳强化剂对极低出生体重早产儿生长发育及喂养不耐受的影响  

Effects of Early Breast Milk Combined with Breast Milk Fortifiers on the Growth,Development and Feeding Intolerance of Extremely Low Birth Weight Premature Infants

作　　者：于翠娟[1] 连英惠 YU Cuijuan;LIAN Yinghui(Department of Children's Healthcare,Qingdao University Affiliated Weihai Municipal Second Hospital,Weihai 264200,China)

机构地区：[1]青岛大学附属威海市立第二医院儿童保健科,山东威海264200

出　　处：《反射疗法与康复医学》2024年第13期95-98,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨早期母乳联合母乳强化剂对极低出生体重早产儿生长发育及喂养不耐受的影响。方法选择2021年8月—2022年9月青岛大学附属威海市立第二医院收治的82例极低出生体重早产儿为研究对象,采用随机数字表法将其分为对照组和观察组,各41例。对照组采取早期母乳喂养,观察组在对照组基础上联合母乳强化剂喂养。比较两组的生长发育指标、营养指标、喂养不耐受情况及并发症发生情况。结果出院1年后,观察组头围、身长均长于对照组,体重大于对照组,组间差异有统计学意义(P<0.05)。喂养3个月后,观察组前白蛋白、白蛋白、总蛋白水平均高于对照组,组间差异有统计学意义(P<0.05)。出院前,观察组喂养不耐受发生率、并发症发生率均低于对照组,组间差异有统计学意义(P<0.05)。结论早期母乳联合母乳强化剂对极低出生体重早产儿进行喂养可有效改善其喂养不耐受情况,可提高早产儿的机体营养状况,并促进生长发育,且可减少并发症的发生。Objective Exploring the effects of early breast milk combined with breast milk fortifiers on the growth,development and feeding intolerance of extremely low birth weight premature infants.Methods A total of 82 cases of extremely low birth weight premature infants admitted to Qingdao University Affiliated Weihai Municipal Second Hospital affiliated from August 2021 to September 2022 were selected as the research subjects,using a random number table method,they were divided into a control group and an observation group,with 41 cases in each group.The control group received early breast milk feeding,while the observation group received feeding combined with breast milk fortifiers on the basis of the control group.Compare the growth and development indicators,nutritional indicators,feeding intolerance,and incidence of complications between two groups.Results After one year of discharge,the observation group had longer head circumference and body length than the control group,and had a higher body weight than the control group,the differences between groups were statistically significant(P<0.05).After 3 months of feeding,the levels of prealbumin,albumin,and total protein in the observation group were higher than those in the control group,the differences between groups were statistically significant(P<0.05).Before discharge,the incidence of feeding intolerance and complications in the observation group was lower than that in the control group,the differences between groups were statistically significant(P<0.05).Conclusion Early breast milk combined with breast milk fortifiers for feeding extremely low birth weight premature infants can effectively improve their feeding intolerance,enhance their nutritional status,promote growth and development and reduce the occurrence of com-plications.

关 键 词：极低出生体重早产儿 早期母乳 母乳强化剂 生长发育 喂养不耐受 营养指标 

分 类 号：R722.6[医药卫生—儿科]