3.0T磁共振弥散张量成像各向异性分数值 表观弥散系数值在脑转移瘤诊断中的临床价值研究  

The clinical value of anisotropic fraction and apparent diffusion coefficient values in the diagnosis of brain metastases using 3.0T magnetic resonance diffusion tensor imaging

作　　者：陈钦力 张文昌[2] 范剑荣 刘振华 Chen Qinli;Zhang Wenchang;Fan Jianrong;Liu Zhenhua(Department of Radiology,Zhangping Hospital,Zhangping 364400,China;Department of Radiology,the Second Hospital of Longyan City,Longyan 364000,China)

机构地区：[1]漳平市医院放射科,漳平364400 [2]龙岩市第二医院放射科,龙岩364000

出　　处：《实用医技杂志》2024年第10期705-708,共4页Journal of Practical Medical Techniques

摘　　要：目的分析3.0 T磁共振扩散张量成像(DTI)各向异性分数(FA)值、表观弥散系数(ADC)值对脑转移瘤(BM)、高级别胶质瘤(HGG)的鉴别诊断价值。方法选定本院2020年1月至2024年4月就诊的120例BM患者设为观察组,以及同期本院就诊的70例HGG患者设为对照组,均给予DTI检查,比较2组肿瘤实性区域以及瘤周水肿区域FA值、ADC值,比较2组DTI影像学特征,绘制受试者工作特征(ROC)曲线,分析FA值、ADC值对BM的诊断效能。结果观察组肿瘤实性区域FA值(0.13±0.05)、ADC值(1.13±0.25)×10^(-3)mm^(2)/s与对照组(0.14±0.05)、(1.12±0.27)×10^(-3)mm^(2)/s比较差异无统计学意义(P>0.05);观察组瘤周水肿区域FA值(0.23±0.06)、ADC值(1.52±0.26)×10^(-3)mm^(2)/s均较对照组(0.14±0.07)、(1.25±0.14)×10^(-3)mm^(2)/s更高(P<0.05)。观察组肿瘤部位与对照组比较差异无统计学意义(P>0.05);观察组瘤内出血、形态规则、坏死囊变、强化方式、瘤周水肿与对照组比较差异无统计学意义(P<0.05)。FA值、ADC值联合诊断BM的曲线下面积(AUC)(95%CI)=0.876(0.841,0.947),FA值、ADC值联合诊断BM的灵敏度(93.02%)较单一检测(72.04%、75.96%)更高(P<0.05),联合检测特异度(82.13%)与单一检测(81.96%、80.04%)比较差异无统计学意义(P>0.05)。结论DTI通过定量检测FA值、ADC值,可提高对BM的诊断灵敏度,在鉴别诊断BM、HGG方面临床价值较高。Objective To analyze the clinical value of anisotropic fraction(FA)and apparent diffusion coefficient(ADC)values in the diagnosis of brain metastases(BM)using 3.0T magnetic resonance diffusion tensor imaging(DTI).Methods A total of 120 BM patients who visited our hospital from January 2020 to April 2024 were selected as the observation group,and 70 high-grade gliomas(HGG)patients who visited our hospital during the same period were selected as the control group.DTI examination was performed on both groups to compare the FA and ADC values of solid tumor areas and peritumoral edema areas,and to compare the DTI imaging characteristics of the two groups.Receiver operating characteristic(ROC)curves were drawn to analyze the diagnostic efficacy of FA and ADC values for BM.Results There was no significant difference in FA value(0.13±0.05)and ADC value(1.13±0.25)×10^(-3)mm^(2)/s between the observation group and the control group(0.14±0.05)and(1.12±0.27)×10^(-3) mm^(2)/s(P>0.05).The FA value(0.23±0.06)and ADC value(1.52±0.26)×10^(-3)mm^(2)/s in the peritumoral edema area of the observation group were higher than those of the control group(0.14±0.07)and(1.25±0.14)×10^(-3)mm^(2)/s(P<0.05).There was no significant difference in tumor location between the observation group and the control group(P>0.05).Comparison of intratumoral bleeding,regular morphology,necrotic cystic changes,enhancement mode,and peritumoral edema between the observation group and the control group(P<0.05).The area under the curve(AUC)for the combined diagnosis of BM by FA and ADC values is 0.876,with a 95%confidence interval of 0.841-0.947.The sensitivity of the combined diagnosis of BM by FA and ADC values(93.02%)is higher than that of single detection(72.04%,75.96%)(P<0.05),and the specificity of the combined detection(82.13%)is compared with that of single detection(81.96%,80.04%)(P>0.05).Conclusion DTI can improve the diagnostic sensitivity of BM by quantitatively detecting FA and ADC values,and has high clinical value in distinguishing

关 键 词：脑弥散张量成像 各向异性分数 表观弥散系数 颅内转移瘤 胶质瘤 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.41[医药卫生—诊断学]