多参数磁共振成像对短暂性脑缺血发作后短期卒中发生的预测价值研究  

The predictive value of multi-parameter magenetic resonance imaging for short-term stroke after transient ischemic attack

作　　者：龚碧云 Gong Biyun(Department of Medical Imaging,Fujian Geriatric Hospital,Fuzhou 350001,China)

机构地区：[1]福建省老年医院医学影像科,福州350001

出　　处：《实用医技杂志》2024年第10期708-712,共5页Journal of Practical Medical Techniques

摘　　要：目的分析多参数磁共振成像(MRI)扫描序列对短暂性脑缺血发作(TIA)后短期卒中发生的预测价值。方法选择2022年1月至12月在我院就诊的80例TIA患者进行研究,均进行多参数MRI检查,包括T_(1)加权成像(T_(1)WI)、T_(2)加权成像(T_(2)WI)、T_(2)液体衰减反转恢复(T_(2)-FLAIR)、弥散加权成像(DWI)。对患者进行为期90 d随访,根据其是否发生卒中分为卒中组与非卒中组,通过单因素、多因素分析TIA后卒中发生的相关MRI危险因素,并绘制受试者工作特征(ROC)曲线分析相关MRI特征预测TIA后卒中发生的临床效能。结果经单因素、多因素分析显示,仅颅内动脉狭窄、颅内颅外多支动脉狭窄、脑室周围白质高信号2级、深部白质高信号2级、DWI阳性、T_(2)血管高信号征阳性为TIA后卒中发生危险因素(P<0.05)。经ROC曲线显示,MRI示颅内颅外多支动脉狭窄、脑室周围白质高信号2级、深部白质高信号2级、DWI阳性对TIA后卒中发生的预测效能良好,其灵敏度分别为50.0%、75.0%、66.7%、75.0%。结论MRI参数见多支动脉狭窄、脑室周围白质高信号、深部白质高信号2级、DWI阳性预测TIA后短期卒中发生的临床效能良好,可为临床早期防治提供依据。Objective To analyze the predictive value of multi-parameter MRI scan sequences for short-term stroke after transient ischemic attack(TIA).Methods A total of 80 patients with transient ischemic attack admitted to our hospital from January 2022 to December 2022 were selected for this study.All patients underwent multi-parameter MRI examination,including T_(1)WI,T_(2)WI,T_(2)-FLAIR and DWI.Patients were followed up for a period of 90 days and divided into stroke group and non-stroke group according to whether they had stroke or not.The MRI risk factors related to stroke after transient ischemic attack were analyzed by univariate and multivariate analysis,and the ROC curve was drawn to analyze the relevant MRI characteristics to predict the clinical efficacy of stroke after(TIA).Results According to univariate and multivariate analysis,only intracranial artery stenosis,intracranial extracranial multi-branch artery stenosis,periventricular white matter hypersignal grade 2,deep white matter hypersignal grade 2,DWI positive,and T_(2) vessel hypersignal sign positive were risk factors for stroke after TIA(P<0.05).According to ROC curve,MRI showed that intracranial extracranial multiple artery stenosis,periventricular white matter high signal level 2,deep white matter high signal level 2,and DWI positive had good predictive efficacy for stroke after TIA,with sensitivity of 50.0%,75.0%,66.7%,75.0%,respectively.Conclusion MRI parameters such as multi-branch artery stenosis,periventricular high white matter signal,deep white matter high signal grade 2 and DWI positive have good clinical efficacy in predicting short-term stroke after TIA,which can provide evidence for early clinical prevention and treatment.

关 键 词：磁共振成像 短暂性脑缺血发作 脑卒中 预测价值 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.31[医药卫生—诊断学]