BiPAP无创呼吸机治疗老年OSAHS患者的疗效及对认知功能和睡眠状况的影响  

Effect of IPAP Non-Invasive Ventilation on Cognitive Function and Sleep Status in Elderly Patients with OSAHS

作　　者：王明珠 朴仁女 刘爽 WANG Ming-zhu;PU Ren-nv;LIU Shuang(Liaoning Jinqiu Hospital,Liaoning Shenyang 110000)

机构地区：[1]辽宁省金秋医院,辽宁沈阳110000

出　　处：《中国医疗器械信息》2024年第22期56-58,共3页China Medical Device Information

摘　　要：目的:探讨老年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者采用BIPAP无创呼吸机治疗的临床疗效。方法:回顾性分析2021年10月~2023年8月接收的126例老年OSAHS患者的临床资料,按照治疗方式将其分组,采用有创呼吸机治疗的为参照组,采用BiPAP无创呼吸机治疗的为研究组,观察两组治疗前后动脉血气指标[动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))]、认知功能[蒙特利尔认知量表(MoCA)评分、简易精神状态量表(MMSE)评分]、睡眠状况[Epworth嗜睡量表(ESS)评分、AHI、总睡眠时间、最长呼吸暂停时间、最低氧饱和度]改善程度。结果:治疗前两组PaCO_(2)、PaO_(2)水平与MMSE、ESS、MoCA评分、AHI指标值、最低血氧饱和度、最长呼吸暂停时间、总睡眠时间以及治疗后的最低氧饱和度差异对比不明显(P>0.05),研究组治疗后PaO_(2)水平、MMSE、MoCA、ESS评分均比参照组高,PaCO_(2)水平低于参照组,AHI指标少于参照组,最长呼吸暂停时间和总睡眠时间也明显比参照组短(P<0.05)。结论:BIPAP无创呼吸机治疗老年OSAHS,能有效改善患者的动脉血气指标、认知功能与睡眠状况,能够有效提升老年患者的生活质量。Objective:To investigate the clinical efficacy of BIPAP non-invasive ventilator in elderly patients with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods:Clinical data of 126 elderly patients with OSAHS received from October 2021 to August 2023 were retrospectively analyzed.They were grouped according to treatment methods,with invasive ventilator treatment as the reference group and BiPAP non-invasive ventilator treatment as the study group.Arterial blood gas index(PaO_(2),PaCO_(2)),cognitive function[Montreal Cognitive Scale(MoCA)score,Simple Mental State Scale(MMSE)score],sleep status[Epworth Lethargy Scale(ESS)score,AHI,total sleep time,EPworth sleep scale(ESS)score before and after treatment were observed in the two groups.Maximum duration of apnea,minimum oxygen saturation]improvement.Results:There were no significant differences between PaCO_(2) and PaO_(2) levels,MMSE,ESS,MoCA score,AHI index value,minimum blood oxygen saturation,longest apnea time,total sleep time,and minimum oxygen saturation after treatment between the two groups before treatment(P>0.05).After treatment,the PaO_(2) level,MMSE,MoCA and ESS scores of the study group were higher than that of the reference group,the PaCO_(2) level was lower than that of the reference group,the AHI index was lower than that of the reference group,and the longest apnea time and total sleep time were also significantly shorter than that of the reference group(P<0.05).Conclusion:BIPAP non-invasive ventilator can effectively improve the arterial blood gas index,cognitive function and sleep status of the elderly patients with OSAHS,and can effectively improve the quality of life of the elderly patients.

关 键 词：BIPAP无创呼吸机 老年OSAHS 认知功能 睡眠状况 

分 类 号：R766[医药卫生—耳鼻咽喉科]