功能双重乳液的制备及应用研究进展  

Progress in preparation and application of functional double emulsions

作　　者：曹强 潘大伟 汪伟[1] 谢锐[1] 巨晓洁[1] 刘壮[1] 褚良银[1] Qiang Cao;Da-Wei Pan;Wei Wang;Rui Xie;Xiao-Jie Ju;Zhuang Liu;Liang-Yin Chu(School of Chemical Engineering,Sichuan University,Chengdu 610065,China)

机构地区：[1]四川大学化学工程学院,成都610065

出　　处：《中国科学：化学》2024年第11期2132-2146,共15页SCIENTIA SINICA Chimica

基　　金：国家自然科学基金资助项目(编号:21991101,22278274)。

摘　　要：双重乳液是一种具有液滴包裹液滴结构的多相体系,其通常具有结构可设计、可包封多样化活性物质等优点,因而在化工、生物、医药等诸多领域具有广泛应用.深入研究功能双重乳液的制备方法,并阐明功能双重乳液结构、组分、尺寸及其均一性的可控性规律,对于实现功能双重乳液的多样化应用具有重要意义.本文主要综述了近年来功能双重乳液的制备方法及其典型应用方面的研究进展,着重介绍了基于膜乳化法、微流控法、相转化法及渗透压驱动法制备双重乳液及相关功能材料,以及纳米双重乳液的可控构建,总结了双重乳液在不同领域的应用研究新进展,并展望了双重乳液结构设计及其在新兴领域的未来发展趋势,从而为实现双重乳液的功能化理性设计提供科学指导.Double emulsions are a kind of multiphase system with inner droplets inside.Because of the advantages of designable structures and encapsulation ability of diversified active substances,it has been widely used in many fields such as chemical industry,biology,and medicine.It is of great significance to study various methods for functional double emulsions preparation,and to elucidate the regulation laws of encapsulation structure,composition,size and uniformity of the resultant functional double emulsions.In this paper,the preparation methods of functional double emulsions and the research progress in typical applications in recent years are systematically reviewed.Specifically,the preparation of double emulsions and their related functional materials based on membrane emulsification,microfluidic emulsification,phase inversion and osmotic-pressure-driven methods are initially introduced,and then the controllable construction of double nanoemulsions is also briefly introduced.Finally,this review summarizes new research progress in the application of double emulsions in different fields,and also looks forward to the rational design of the structures of double emulsions and its future development trend in the emerging fields.This review could provide scientific guidance for the design of functional double emulsions.

关 键 词：双重乳液 微流控 纳米乳液 相转化 膜乳化 

分 类 号：O648.23[理学—物理化学]