发热待查的病原学诊断技术及研究进展  

The pathogenetic diagnostic techniques and research progress in patients with fever of unknown origin

作　　者：宋小燕 吴瑞珊 赵文忠 SONG Xiaoyan;WU Ruishan;ZHAO Wenzhong(Clinical lab,Guangdong Provincial Reproductive Science Institute(Guangdong Provincial Fertility Hospital),NHC Key Laboratory of Male Reproduction and Genetics,Guangzhou 510600,Guangdong,China)

机构地区：[1]广东省生殖科学研究所(广东省生殖医院),国家卫生健康委员会男性生殖与遗传重点实验室检验科,广东广州510600

出　　处：《实用医学杂志》2024年第23期3405-3410,共6页The Journal of Practical Medicine

基　　金：广东省医学科研基金项目(编号:B2023275)。

摘　　要：发热(fever)是机体对外来病原或物质的常见病理生理反应,也是疾病进展中最重要的临床表现之一。发热待查(fever of unknown origin,FUO)的诊断是临床上的难题之一,而感染性疾病(infectious diseases,ID)是FUO最常见的病因之一。通过病原学诊断技术,可以快速确定感染的发生和性质。而最新的诊断技术,更是加快了病原微生物的识别及药敏分析,尽早判断疾病,给予精准治疗,促使患者尽快恢复健康。该文综述了FUO的病因、引起发热的ID病原学诊断方法和研究进展,旨在为准确快速诊断FUO提供参考。Fever is a common pathophysiological response of the body to foreign pathogens or substances,and it is also one of the most important clinical manifestations in the progression of diseases.The diagnosis of fever of unknown origin(FUO)is a clinical challenge,and infectious diseases(ID)are among the most common causes of FUO.Through diagnostic techniques in microbiology,the occurrence and nature of infections can be rapidly determined.The latest diagnostic technologies have accelerated the identification of pathogenic microorganisms and antimicrobial susceptibility analysis,enabling early disease assessment,precise treatment,and facilitating the rapid recovery of patients.This article reviews the causes of FUO,infectious diseases that cause fever,microbio⁃logical diagnostic methods,and research progress,aiming to provide reference for the accurate and rapid diagnosis of FUO.

关 键 词：发热待查 感染性疾病 病原学诊断 

分 类 号：R441.3[医药卫生—诊断学]