基于全健康理念的微生物耐药性监测体系研究进展  

Research on the antimicrobial resistance monitoring system based on the One Health concept

作　　者：李敏[1] 姜天翔 陈伟叶 胡增运 郭晓奎[1] 朱泳璋[1] LI Min;JIANG Tianxiang;CHEN Weiye;HU Zengyun;GUO Xiaokui;ZHU Yongzhang(School of Global Health,Chinese Center for Tropical Diseases Research,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China;School of Public Health,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院-国家热带病研究中心全球健康学院,上海200025 [2]上海交通大学医学院公共卫生学院,上海200025

出　　处：《中国热带医学》2024年第11期1293-1300,共8页China Tropical Medicine

基　　金：国家自然科学基金项目(No.32170141)。

摘　　要：抗微生物药物耐药性(antimicrobial resistance,AMR)被认为是全球十大公共卫生威胁之一。基于全健康(One Health)策略应对微生物耐药性已成为全球共识。其中,AMR系统监测作为AMR应对策略的基石,具有举足轻重的地位。本文深入分析了中国、英国、美国和欧盟基于全健康理念进行AMR监测的现状和进展,并全面比较了这些国家和欧盟AMR监测系统的异同。研究表明,跨国家、跨地区和跨部门的AMR监测合作正日益增强,然而,不同国家和地区之间仍然存在显著差异。值得一提的是,大多数AMR监测系统优先考虑人类和动物健康,对于环境领域的监测则相对不足。鉴于当前形势,中国仍需继续在人类、动物、食品和环境等各个领域推进标准化的AMR监测数据共享和整合,努力构建全面、系统的“全链条”AMR监测体系,以更好应对这一全球公共卫生挑战。Antimicrobial resistance(AMR),is regarded as one of the top 10 global public health threats.Addressing AMR through the One Health strategy has become a global consensus.AMR monitoring plays a crucial role as the cornerstone of AMR response strategies.This study thoroughly analyzed current situation and progress of AMR monitoring based on the One Health concept in China,the United Kingdom,the United States,and the European Union,and comprehensively compared the similarities and differences of AMR monitoring systems across these countries and regions.The research found that crossnational,cross-regional,and cross-sectoral cooperation in AMR monitoring is increasingly strengthening.However,notable discrepancies still exist among different countries and regions.Notably,most AMR monitoring systems prioritize human and animal health,with relatively insufficient monitoring in the environmental sector.Given the current landscape,China still needs to continue to promote standardized AMR monitoring data sharing and integration across the human,animal,food,and environmental fields,striving to construct a comprehensive and systematic"whole-chain"AMR monitoring system to better tackle this global public health challenge effectively.

关 键 词：微生物耐药性 微生物耐药性监测体系 全健康 

分 类 号：R446.5[医药卫生—诊断学]