基于CiteSpace的HIV/AIDS患者合并恶性肿瘤研究热点可视化分析  

Visualization analysis of research hotspots on HIV/AIDS patients with malignant tumors based on CiteSpace

作　　者：罗琳琳 胡新宁 张欣欣[1,2] 张悦 金艳涛[1,3] 许前磊 LUO Linlin;HU Xinning;ZHANG Xinxin;ZHANG Yue;JIN Yantao;XU Qianlei(AIDS Clinical Research Center,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,Henan,Chian;Henan University of Chinese Medicine,Zhengzhou 450046,Henan,Chian;Henan Provincial Key Laboratory of Traditional Chinese Medicine Prevention and Treatment for Viral Diseases,Zhengzhou 450000,Henan,China)

机构地区：[1]河南中医药大学第一附属医院艾滋病临床研究中心,郑州450000 [2]河南中医药大学,郑州450046 [3]河南省病毒性疾病中医药防治重点实验室,郑州450000

出　　处：《中国艾滋病性病》2024年第11期1157-1162,共6页Chinese Journal of Aids & STD

基　　金：中原英才计划(育才系列)中原青年拔尖人才(ZYYCYU202012153);河南省自然科学基金项目(222300420059);河南省科技研发计划联合基金(232301420089);河南省中医药科学研究专项课题(2022ZY1032)。

摘　　要：目的基于CiteSpace对国内外HIV/AIDS合并恶性肿瘤患者的研究现状、热点和趋势进行可视化分析,探索未来研究方向。方法检索建库至2023年12月31日Web of Science核心合集(WOS)和中国知网(CNKI)中HIV/AIDS合并恶性肿瘤患者的相关文献,借助CiteSpace对文献进行可视化分析。结果共纳入文献6064篇(其中CNKI 161篇,WoS 5903篇)。发文量最多的国家为美国(2921篇)。中文文献的关键词、聚类、突现词显示临床特征、肿瘤类型及治疗方案是主要研究方向。英文文献的关键词、聚类、突现词图谱显示其主要围绕恶性肿瘤的流行病学、发病机制、生物标志物和新型治疗策略方面。结论国内外研究方向各有侧重,恶性肿瘤的流行病学、发病机制和治疗是共同的研究热点和趋势。未来研究应结合人工智能、大数据等现代科学技术,深入挖掘HIV/AIDS患者合并恶性肿瘤机制及相关生物标志物,提升HIV/AIDS患者合并恶性肿瘤防治水平。Objective To perform a visualization analysis of the research status,hotspots and trends concerning HIV/AIDS patients with malignant tumors both domestically and internationally based on CiteSpace,and to explore future research directions.Methods Literature related to HIV/AIDS patients with malignant tumors was retrieved from the Web of Science Core Collection(WOS)and China National Knowledge Infrastructure(CNKI)databases,covering the period up to 31 December,2023.CiteSpace was used to visualize and analyze the literature.Results A total of 6064publications were included(161 from CNKI and 5903 from WOS).The United States had the highest publication volume(2921).Keywords,clusters,and burst terms in Chinese literature indicating clinical characteristics,tumor types,and therapeutic regimens were the main research directions.Keywords,clusters,and burst term maps in English literature were mainly focused on the epidemiology,pathogenesis,biomarkers,and novel therapeutic strategies for malignant tumors.Conclusions The research focus differs between domestic and international studies,but epidemiology,pathogenesis,and treatment of malignant tumors remain common research hotspots and trends.Future research should integrate modern scientific technologies,such as artificial intelligence and big data,to further explore the mechanisms and biomarkers of HIV/AIDS-associated malignancies,thereby improving the level of prevention and treatment for this populations.

关 键 词：艾滋病患者 恶性肿瘤 可视化分析 

分 类 号：R373.9[医药卫生—病原生物学]