常见类型神经退行性痴呆的神经影像学表现  

Neuroimaging findings of common types of neurodegenerative dementias

作　　者：李奇骏 王俊山 袁晶 崔瑞雪 LI Qijun;WANG Junshan;YUAN Jing;CUI Ruixue(Department of Nuclear Medicine,Peking Union Medical College Hospital,CAMS&PUMC,Beijing 100730,China;Department of Neurology,Peking Union Medical College Hospital,CAMS&PUMC,Beijing 100730,China)

机构地区：[1]中国医学科学院、北京协和医学院、北京协和医院核医学科,北京100730 [2]中国医学科学院、北京协和医学院、北京协和医院神经科,北京100730

出　　处：《基础医学与临床》2024年第12期1741-1745,共5页Basic and Clinical Medicine

基　　金：中央高水平医院临床科研专项(2022-PUMCH-B-070,2022-PUMCH-B-018)。

摘　　要：神经退行性痴呆是以认知功能受损为主要临床表现的一组综合征,可有多种不同的病理基础。神经影像学检查结合临床表现有助于对痴呆进行病因学诊断及鉴别诊断。本文简要介绍了阿尔茨海默病、额颞叶痴呆以及路易体痴呆3种常见神经退行性痴呆的神经影像学(MRI、PET和SPECT)表现。Neurodegenerative dementias are a group of clinical syndromes manifested with impairment of cognitive functions with various pathological etiologies.Neuroimaging along with clinical presentations can make etiological diagnoses and support differentiate diagnosis of various dementias.In this article,we briefly introduced the MRI,PET and SPECT differential patterns in the three most common neurodegenerative dementias including Alzheimer′s disease,frontotemporal lobe dementia and Lewy body dementia.

关 键 词：神经影像学 正电子发射断层 阿尔茨海默病 额颞叶痴呆 路易体痴呆 

分 类 号：R445.2[医药卫生—影像医学与核医学] R445.5[医药卫生—诊断学]