巴西诺卡菌感染免疫功能正常患者致原发性皮肤诺卡菌病1例  

Primary cutaneous nocardiosis caused by Nocardia brasiliensis in an immunocompetent patient:Acasereport

作　　者：胡晓倩 张维[1] 赵欣[2] HU Xiaoqian;ZHANG Wei;ZHAO Xin(Department of Dermatology,the Northwest University First Hospital,Xi'an 710043,China)

机构地区：[1]西北大学第一医院皮肤科,西安710043 [2]西北大学第一医院检验科

出　　处：《实用皮肤病学杂志》2024年第5期317-320,共4页Journal of Practical Dermatology

摘　　要：报道1例免疫功能正常患者感染巴西诺卡菌致原发性皮肤诺卡菌病。患者男,68岁,左下肢红肿、破溃伴疼痛7 d。皮肤科检查:左下肢红斑、肿胀,触之疼痛,皮温升高,左侧外踝可见两处皮肤破溃,有脓液、脓血渗出,胫前散在黯红色斑片,皮肤触之硬。予以一般细菌培养、鉴定及质谱分析,最终鉴定为巴西诺卡菌。诊断:原发性皮肤诺卡菌病。予以脓肿切开、复方磺胺甲噁唑抗感染治疗,6个月后随访,患者皮损愈合良好,未复发。A case of primary cutaneous nocardiosis caused by Nocardia brasiliensis in an immunocompetent patient was reported.A 68-year-old male patient presented with redness,swelling,ulcers and pain on the left lower limb for 7 days.Dermatological examination showed that redness and swelling were observed in the left lower limb,with tenderness and increased skin temperature.Two areas of skin ulceration with purulent and serosanguinous exudate were noted over the left lateral malleolus.Scattered dark red patches were present on the anterior shin,with the skin feeling indurated.The results of routine bacterial culture,identification,and mass spectrometry analysis ultimately revealed infection with Nocardia brasiliensis.The diagnosis of primary cutaneous nocardiosis caused by Nocardia brasiliensis was made.The wound improved following abscess incision and drainage,along with anti-infection treatment with sulfamethoxazole and trimethoprim.The patient claimed that the wound recovered well and there was no recurrence after 6 months of follow-up.

关 键 词：诺卡菌病 皮肤 巴西诺卡菌 复方磺胺甲噁唑 

分 类 号：R754.9[医药卫生—皮肤病学与性病学]