经鼻间歇正压通气与经鼻持续正压通气对呼吸窘迫综合征早产儿治疗状况和住院时间的影响  

Effect of nasal continuous positive airway pressure and nasal intermittent positive pressure ventilation on the treatment status and hospitalization time of premature infants with respiratory distress syndrome

作　　者：童童 洪海玲 陈凯 TONG Tong;HONG Hailing;CHEN Kai(Department of Pediatrics,Shangrao Maternal and Child Health Hospital,Shangrao,Jiangxi,334000,China;Department of Neonatology,Shangrao Maternal and Child Health Hospital,Shangrao,Jiangxi,334000,China)

机构地区：[1]上饶市妇幼保健院儿科,江西上饶334000 [2]上饶市妇幼保健院新生儿科,江西上饶334000

出　　处：《当代医学》2024年第18期139-142,共4页Contemporary Medicine

基　　金：江西省卫生健康委科技计划(202312310)。

摘　　要：目的探讨经鼻间歇正压通气(nasal intermittent positive pressure ventilation,NIPPV)对呼吸窘迫综合征(respiratory distress syndrome,RDS)与经鼻持续正压通气(nasal continuous positive airway pressure,NCPAP)早产儿治疗状况及住院时间的影响。方法选取2020年2月至2022年7月于上饶市妇幼保健院新生儿科收治的80例RDS早产儿作为研究对象,按照入院顺序分为参照组与研究组,每组40例。参照组实施NCPAP治疗,研究组实施NIPPV治疗,比较两组无创通气时间、用氧时间、住院时间及血气指标[pH值、动脉血二氧化碳分压(partial pressure of carbon dioxide in artery,PaCO_(2))、动脉血氧分压(arterial partial pressure of oxygen,PaO_(2))、P/F]及两组并发症发生情况比较。结果研究组无创通气时间、用氧时间、住院时间均短于参照组,差异有统计学意义(P<0.05)。治疗后,两组PaCO_(2)均低于治疗前,PaO_(2)、P/F均高于治疗前,且研究组PaCO_(2)低于参照组,PaO_(2)、P/F均高于参照组,差异有统计学意义(P<0.05),两组组内治疗前后及组间pH值比较差异无统计学意义。研究组并发症总发生率低于参照组,差异有统计学意义(P<0.05)。结论NIPPV用于RDS早产儿治疗中的价值优于NC-PAP,改善患儿治疗状况及血气指标方面的表现更佳,且可同步降低辅助通气相关并发症风险,具有临床推广价值。Objective To investigate the effects of nasal intermittent positive pressure ventilation(NIPPV)and nasal continuous positive airway pressure(NCPAP)on the treatment status and hospitalization time of premature infants with respiratory distress syndrome(RDS).Methods 80 premature infants with RDS admitted to the Department of Neonatology,Shangrao Maternal and Child Health Hospital from February 2020 to July 2022 were selected as the research subjects,they were divided into the reference group and the study group according to the order of admission,with 40 cases in each group.The reference group was treated with NCPAP,and the study group was treated with NIPPV.The non-invasive ventilation time,oxygen use time,hospitalization time,blood gas indexes(pH value,partial pressure of carbon dioxide in artery[PaCO_(2)],arterial partial pressure of oxygen[PaO_(2)],P/F)and complications were compared between the two groups.Results The non-invasive ventilation time,oxygen use time and hospitalization time in the study group were shorter than those in the reference group,and the differences were statistically significant(P<0.05).After treatment,PaCO_(2)of the two groups were lower than that before treatment,PaO_(2)and P/F were higher than those before treatment,the PaCO_(2)in the study group was lower than that in the reference group,PaO_(2)and P/F were higher than those in the reference group,and the differences were statistically significant(P<0.05),there was no significant differences in pH value of the two groups before and after treatment as well as between two groups.The total incidence of complications in the study group was lower than that in the reference group,and the difference was statistically significant(P<0.05).Conclusion The value of NIPPV in the treatment of RDS in premature infants is better than that of NCPAP,it has better performance in improving the treatment status and blood gas index of children,and can simultaneously reduce the risk of complications related to assisted ventilation,which has clinical promot

关 键 词：呼吸窘迫综合征 持续正压通气 间歇正压通气 住院时间 并发症 

分 类 号：R722.6[医药卫生—儿科]