前锯肌平面阻滞对老年病人胸腔镜下外科房颤消融术后炎症因子的影响  

Effect of serratus anterior plane block on inflammatory factors in elderly patients undergoing thoracoscopic surgical ablation for atrial fibrillation

作　　者：许佩龙 王敏[1] 陈宇 陈晓东 XU Peilong;WANG Min;CHEN Yu;CHEN Xiaodong(Department of Anesthesiology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院麻醉与围术期医学科,江苏省南京市210029

出　　处：《实用老年医学》2024年第12期1242-1245,共4页Practical Geriatrics

摘　　要：目的评估超声引导下前锯肌平面阻滞(SAPB)联合全身麻醉对行胸腔镜下外科房颤消融术老年病人炎症因子水平的影响。方法本研究为单中心、前瞻性、随机对照试验,共纳入80例老年病人,随机分配至SAPB组和对照组,SAPB组术前行超声引导下双侧SAPB(0.375%罗哌卡因20 mL),对照组术前不行阻滞,比较2组术后24 h内炎症因子水平的变化。结果与对照组相比,SAPB组的IL-6和hs-CRP水平显著下降(P<0.01)。此外,SAPB组病人术后部分生命体征指标更加稳定,疼痛评分显著低于对照组(P<0.01)。结论SAPB联合全身麻醉能够有效降低胸腔镜下外科房颤消融术病人术后炎症反应,有利于术后恢复。Objective To evaluate the effect of ultrasound-guided serratus anterior plane block(SAPB)combined with general anesthesia on postoperative inflammatory factors in the elderly patients undergoing thoracoscopic surgical ablation for atrial fibrillation.Methods This study was a single-center,prospective,randomized controlled trial involving 80 elderly patients,who were randomly divided into SAPB group and control group.The SAPB group received preoperative ultrasound-guided bilateral SAPB(20 mL of 0.375%ropivacaine on each side),while the control group did not receive nerve block.The levels of the inflammatory factors within 24 hours after the operation were compared between the two groups.Results The levels of interleukin-6(IL-6)and high sensitivity C-reaction protein(hs-CRP)in the SAPB group were significantly lower than those in the control group(P<0.01).The SAPB group showed more stable postoperative vital signs and significantly lower pain scores compared to the control group(P<0.01).Conclusions SAPB combined with general anesthesia can effectively reduce postoperative inflammation in the elderly patients undergoing thoracoscopic surgical ablation for atrial fibrillation,and improve the postoperative recovery.

关 键 词：神经阻滞 房颤 炎症因子 老年人 手术消融 

分 类 号：R614.4[医药卫生—麻醉学]