双层探测器光谱CT在肝细胞癌评估中的应用  

Dual-Layer Detector Spectral CT in the Evaluation of Hepatocellular Carcinoma

在线阅读下载全文

作  者:陈勉 吴方明 王劲[3] 李辉 Chen Mian;Wu Fangming;Wang Jin;Li Hui(Department of Radiology,Henan Provincial People's Hospital,Zhengzhou Henan 450003,China;Department of Comprehensive Intervention,Henan Provincial People's Hospital,Zhengzhou Henan 450003,China;Department of Interventional Radiology,Jiaozuo People's Hospital,Jiaozuo Henan 454000,China)

机构地区:[1]河南省人民医院放射科,河南郑州450003 [2]河南省人民医院综合介入科,河南郑州450003 [3]焦作市人民医院放射介入科,河南焦作454000

出  处:《临床研究》2024年第12期145-148,共4页Clinical Research

基  金:康博刀治疗肝肿瘤的免疫环境重塑及免疫响应临床研究(2020YFC0122305)。

摘  要:目的评估双层探测器光谱CT(DLCT)虚拟单能级图像在肝细胞癌(HCC)评估中的价值。方法回顾性分析2023年7月至2023年10月在河南省人民医院放射科检查的30例肝细胞癌患者临床影像资料。所有患者均行上腹部三期(平扫、动脉期、门静脉期)扫描。利用后处理工作站将光谱图像数据重建,获得四组虚拟单能级图像(40 keV、50 keV、60 keV和120 keV)和120 kV混合能量图像。对五组进行图像分析,采用了客观评分指标,包括CT值、信噪比(SNR)、对比噪声比(CNR),及主观评分进行图像质量评价。结果40 keV、50 keV、60 keV、120 keV、120 kV的主观得分分别为(4.54±0.29)分、(3.78±0.17)分、(3.30±0.46)分、(2.28±0.24)分、(3.02±0.24)分,两两对比差异均有统计学意义(P<0.05)。其中,40 keV的得分最高,随着能量级的增加,图像质量的主观得分逐渐减小,图像质量评分逐级降低,120 kV的图像质量高于120 keV。不同的能量级下,各能量级的图像指标有较大差异。见表2。40 keV图像CT值、CNR、SNR均明显高于50 keV、60 keV、120 keV、120 kV,差异均有统计学意义(P<0.05)。随着能量级(40 keV、50 keV、60 keV、120 keV)的增加,病灶的CNR、SNR逐渐降低。120 KV的图像CT值、CNR、SNR位于60 keV与120 keV的图像CT值、CNR、SNR之间,提示120 kV时,患者病灶的显示质量介于60 keV与120 keV之间;在40 keV时,患者病灶的显示质量优于更高的能量级,且在40 keV、50 keV、60 keV与120 keV能量级下,图像质量与能量级的大小呈反比。结论双层探测器CT低keV虚拟单能级成像可提高肝细胞癌病灶的CT值和SNR、CNR,且具有较好的图像质量评分,能够在动脉期更好的显示肝细胞癌病灶。Objective To evaluate the value of dual-layer detector spectral CT(DLCT)virtual monoenergetic images in the assessment of hepatocellular carcinoma(HCC).Methods A retrospective analysis was conducted on the clinical imaging data of 30 HCC patients who underwent examination in the Department of Radiology at the Henan Provincial People's Hospital between July 2023 and October 2023.All patients underwent a triphasic scan(plain scan,arterial phase,and portal venous phase)of the upper abdomen.Spectral image data was reconstructed using post-processing workstations to obtain four sets of virtual monoenergetic images(40 keV,50 keV,60 keV,and 120 keV)and 120 kV mixed energy images.Image analysis was performed on these five groups using objective evaluation metrics including CT value,signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),as well as subjective scoring for image quality assessment.Results The subjective scores for 40 keV,50 keV,60 keV,120 keV,and 120 kV were(4.54±0.29),(3.78±0.17),(3.30±0.46),(2.28±0.24),and(3.02±0.24)respectively,with statistically significant differences in pairwise comparisons(P<0.05).Among them,the 40 keV received the highest score,and as the energy level increased,the subjective score for image quality decreased progressively,indicating that the image quality score decreased with increasing energy levels,with the 120 kV image quality being higher than that of 120 keV.The image indicators at different energy levels showed significant variation.At 40 keV,the image CT value,CNR,and SNR were significantly higher than those at 50 keV,60 keV,120 keV,and 120 kV,with statistically significant differences(P<0.05).As the energy levels increased(40 keV,50 keV,60 keV,120 keV),the CNR and SNR of the lesions gradually decreased.The CT value,CNR,and SNR at 120 kV were between those at 60 keV and 120 keV,suggesting that at 120 kV,the display quality of the patient's lesion was intermediate between 60 keV and 120 keV;at 40 keV,the display quality of the patient's lesion was superior to higher ener

关 键 词:肝细胞癌 体层摄影术 图像质量 光谱CT X线计算机 

分 类 号:R445.1[医药卫生—影像医学与核医学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象