肝移植治疗不可切除性结直肠癌肝转移的研究进展  

Research progress in the treatment of liver transplantation for unresectable colorectal cancer liver metastases

作　　者：孙岩岩 张骊[1,2,3,4] 陈池义 蒋文涛 SUN Yanyan;ZHANG Li;CHEN Chiyi;JIANG Wentao(Department of Liver Transplantation,Tianjin First Central Hospital,Tianjin 300192,China;Tianjin Key Laboratory of Molecular Diagnosis and Treatment of Liver Cancer;Tianjin Key Laboratory for Organ Transplantation;Tianjin Research Institute of Transplant Medicine;Department of Liver Cancer,Tianjin First Central Hospital)

机构地区：[1]天津市第一中心医院肝移植科,300192 [2]天津市肝癌分子诊断与治疗重点实验室 [3]天津市器官移植重点实验室 [4]天津市器官移植研究中心 [5]天津市第一中心医院肝脏肿瘤科

出　　处：《天津医药》2024年第12期1335-1340,共6页Tianjin Medical Journal

基　　金：天津市教委科研计划一般项目(2023YXZX08);天津市卫生健康委员会重点学科专项(TJWJ2022XK016)。

摘　　要：结直肠癌转移是患者病情进展和死亡的主要原因。虽然手术切除是治疗肝转移结直肠癌的首选方法,但对于不可切除的结直肠癌肝转移患者,肝移植作为一种治疗途径,已经得到了广泛的关注。近年来,越来越多的临床试验聚焦于肝移植治疗不可切除性结直肠癌肝转移的适应证。该文从肝移植的适应证、禁忌证及其优势方面,系统性地总结了肝移植在不可切除性结直肠癌肝转移中的研究进展。Metastasis of colorectal cancer is the primary cause of progression and mortality.Although surgical resection is the preferred method for liver metastasis of colorectal cancer,liver transplantation,as a treatment approach,has attracted widespread attention for patients with unresectable colorectal cancer liver metastases.Recently,an increasing number of clinical trials have focused on the indications for liver transplantation in the treatment of unresectable colorectal cancer liver metastases.Therefore,we systematically summarize the progress of liver transplantation in the application of unresectable colorectal cancer liver metastasis from the aspects of indications,contraindications and advantages over traditional treatment methods.

关 键 词：结直肠肿瘤 结直肠癌肝转移 肝移植 

分 类 号：R617[医药卫生—外科学]