脓毒症性凝血病诊疗中国专家共识(2024版)  

Chinese expert consensus on the diagnosis and treatment of sepsis-induced coagulopathy(2024 edition)

作　　者：宋景春 丁仁彧[2] 吕奔 梅恒[4] 王岗[5] 张伟 周静[7] 郭军[8] 中国医药教育协会血栓与止血危重病专业委员会 全军重症医学专业委员会 Song Jing-Chun;Ding Ren-Yu;Lyu Ben;Mei Heng;Wang Gang;Zhang Wei;Zhou Jing;Guo Jun;Chinese Society ofThrombosis;Hemostasis and Critical Care;Chinese Medicine Education AssociationChinese People's Liberation Army ProfessionalCommittee of Critical Care Medicine(Department of Critical Care Medicine,the 908th Hospital of the PLA Joint Logistic Support Force,Nanchang,Jiangxi 330002,China;Department of Critical Care Medicine,the First Affiliated Hospital of Chinese Medical University,Shenyang,Liaoning 110001,China;Department of Hematology,the Second Xiangya Hospital,Central South University,Changsha,Hunan 410011,China;Department of Hematology,Union Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China;Department of Critical Care Medicine,the Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,Shaanxi 710004,China;Department of Emergency,the 900th Hospital of the PLA Joint Logistic Support Force,Fuzhou,Fujian 350002,China;Department of Laboratory Medicine,8Department of Critical Care Medicine,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China;不详)

机构地区：[1]解放军联勤保障部队第908医院重症医学科,江西南昌330002 [2]中国医科大学附属第一医院重症医学科,辽宁沈阳110001 [3]中南大学湘雅二医院血液科,湖南长沙410011 [4]华中科技大学同济医学院附属协和医院血液科,湖北武汉430030 [5]西安交通大学第二附属医院重症医学科,陕西西安710004 [6]解放军联勤保障部队第900医院急诊科,福建福州350002 [7]四川大学华西医院实验医学科,四川成都610041 [8]四川大学华西医院重症医学科,四川成都610041 [9]不详

出　　处：《解放军医学杂志》2024年第11期1221-1236,共16页Medical Journal of Chinese People's Liberation Army

摘　　要：脓毒症性凝血病(SIC)是脓毒症导致的血管内皮损伤和凝血紊乱,是导致脓毒症患者死亡的重要因素。对SIC实现早期诊断和治疗有望改善患者的预后。2019年国际血栓止血学会(ISTH)颁布了首部SIC诊疗指南,但我国尚无相关规范。因此,中国医药教育协会血栓与止血危重病专业委员会和全军重症医学专业委员会共同编写了《脓毒症性凝血病诊疗中国专家共识(2024版)》。该共识包括发病机制、分型、实验室评估、诊断和治疗等5个部分,共14条推荐意见,以便指导相应的临床工作。Sepsis-induced coagulopathy(SIC),a critical and potentially lethal condition arising from sepsis,results in endothelial damage and significant coagulation dysregulation,making it a major factor contributing to mortality among sepsis patients.Early diagnosis and treatment of SIC are expected to improve the prognosis of sepsis patients.In 2019,the International Society on Thrombosis and Hemostasis(ISTH)issued the first guidelines for the diagnosis and treatment of SIC,but there are no corresponding protocols in China.Therefore,Chinese Society of Thrombosis,Hemostasis and Critical Care,Chinese Medicine Education Association,and Chinese People's Liberation Army Professional Committee of Critical Care Medicine jointly formulated the "Chinese Expert Consensus on the Diagnosis and Treatment of Sepsis-induced Coagulopathy (2024 edition). " This consensusincludes 5 parts: pathogenesis, classification, laboratory approaches, diagnosis and treatment, with a total of 14 evidence-basedrecommendations to guide clinical practice.

关 键 词：脓毒症 凝血病 免疫血栓 血栓炎症 表型 抗凝 

分 类 号：R459.7[医药卫生—急诊医学]