重视肢端肥大症的并发症筛查与管理  

Emphasizing the screening and management of complications in acromegaly

作　　者：沈如飞 郑宏庭 Shen Ru-Fei;Zheng Hong-Ting(Department of Endocrinology,the Second Affiliated Hospital of Army Medical University,Chongqing 400037,China)

机构地区：[1]陆军军医大学第二附属医院内分泌科,重庆400037

出　　处：《解放军医学杂志》2024年第11期1266-1271,共6页Medical Journal of Chinese People's Liberation Army

摘　　要：肢端肥大症可引起心血管系统、呼吸系统、消化系统、内分泌系统等多个系统的慢性并发症,增加患者的死亡风险,明显缩短患者的预期寿命,而及时筛查、早期诊治可显著改善患者的预后,还能间接反映医院或团队的诊疗水平。临床交流和调研发现,在临床实践过程中,医师常因受到时间、经济、患者依从性等多种因素的影响而未能对肢端肥大症的并发症做到全面筛查。本文借鉴国内外多部专家共识和指南,并结合国内实际情况,从肢端肥大症并发症的发生情况、筛查时机、治疗方式、长期监测和严格管理等方面,归纳总结肢端肥大症并发症的筛查与管理要点,强调临床诊治工作的规范化、精准化和个性化,以期全面提高我国肢端肥大症的诊治水平,提高患者的生存率并改善其生活质量。Acromegaly can cause chronic complications in multiple systems such as the cardiovascular,respiratory,digestive,and endocrine systems,increasing the risk of death and significantly shortening the patient's life expectancy.Timely screening and early diagnosis and treatment can significantly improve the prognosis of patients and indirectly reflect the level of diagnosis and treatment of hospitals or teams.Clinical communication and research have revealed that physicians,in the course of clinical practice,are frequently constrained by factors such as time,economic considerations,and patient compliance,which hinder their ability to perform comprehensive screening for acromegaly-related complications.This review draws on expert consensuses and guidelines from both domestic and international sources,integrating them with the specific realities of China,to provide a comprehensive summary of the key aspects of screening and management for acromegaly-related complications.These aspects include the incidence of complications,optimal timing for screening,treatment approaches,long-term monitoring,and strict management protocols.It emphasizes standardization,precision,and personalization in clinical diagnosis and treatment work,aiming to comprehensively improve the diagnosis and treatment level of acromegaly in China,enhance the survival rate of patients,and improve their quality of life.

关 键 词：肢端肥大症 并发症 筛查 管理 

分 类 号：R58[医药卫生—内分泌]