基于双苯并咪唑Zn(Ⅱ)配合物的合成和抗菌性能的综合化学实验设计  

Comprehensive Chemical Experiment Design on Synthesis and Antibacterial Activity of A Bisbenzimidazole Zinc(Ⅱ)Complex

作　　者：苗金玲[1] 崔玉[1] 范迎菊[1] 聂永[1] 刘子建 MIAO Jinling;CUI Yu;FAN Yingju;NIE Yong;LIU Zijian(College of Chemistry and Chemical Engineering,University of Jinan,Shandong Jinan 250022,China)

机构地区：[1]济南大学化学化工学院,山东济南250022

出　　处：《广州化工》2024年第23期200-203,共4页GuangZhou Chemical Industry

基　　金：山东省自然科学基金(编号:ZR2020MB001);济南大学教学研究项目(编号:J2130)。

摘　　要：苯并咪唑类化合物因其独特的化学结构,在医药领域展现出广泛的应用潜力,特别是在抗菌、抗病毒和抗炎等方面的表现尤为突出。最新研究结果表明一例双苯并咪唑Zn(Ⅱ)配合物具有良好的抗菌活性。该化合物的合成和抗菌活性研究不仅涵盖了有机化学、无机化学、分析化学、仪器分析四个化学专业的理论基础和实验技术,而且涉及生物学的学科知识。将双苯并咪唑Zn(Ⅱ)配合物的合成及其抗菌活性的研究设计成综合实验,不仅拓宽了学生的知识视野,而且提升了学生将理论知识与实践技能相结合的综合应用能力,同时也激发了他们对科学研究的兴趣和热情,为未来的科研工作打下坚实的基础。Benzimidazole compounds,due to their unique chemical structures,have shown extensive potential for applications in the medical field,particularly in antibacterial,antiviral and anti-inflammatory aspects.The latest research results indicate that a bisbenzimidazole Zn(Ⅱ)complex demonstrates good antibacterial activity.The synthesis and antibacterial activity study of this compound not only covers the theoretical basis and experimental techniques of the four chemical majors of organic chemistry,inorganic chemistry,analytical chemistry and instrumental analysis,but also involves knowledge of biology.Designing the synthesis and antibacterial activity of a bisbenzimidazole Zn(Ⅱ)complex as a comprehensive experiment not only broadens students knowledge horizons,but also enhances their comprehensive application ability to combine theoretical knowledge with practical skills.It also stimulates their interest and enthusiasm for scientific research,laying a solid foundation for future scientific research work.

关 键 词：实验教学 苯并咪唑 配合物 综合实验 抗菌活性 

分 类 号：G642.0[文化科学—高等教育学]