Advancing the art of mosquito control: the journey of the sterile insect technique against Aedes aegypti in Cuba  

作　　者：Rene Gato Zulema Menendez Misladys Rodriguez Gladys Gutierrez-Bugallo Maria del Carmen Marquetti 

机构地区：[1]不详

出　　处：《Infectious Diseases of Poverty》2024年第4期96-96,共1页贫困所致传染病（英文）

摘　　要：Background Aedes aegypti,the primary vector of dengue,chikungunya,and Zika viruses,poses a significant public health threat worldwide.Traditional control methods using insecticides are increasingly challenged by resistance and environmental concerns.The sterile insect technique(SIT)offers an eco-friendly alternative that has been suc-cessfully applied to other insect pests.This article aims to briefly review Ae.aegypti management in Cuba,highlighting the accomplishments,challenges,and future directions of the SIT.Main body Here we provide a brief summary of the extensive history of Ae.aegypti control efforts in Cuba.After a successful eradication campaign in the 1980s,a resurgence of dengue cases has been observed in recent years,suggesting that traditional control methods may have limited effectiveness under current conditions.In response,Cuba initiated a phased approach to develop and evaluate the feasibility of SIT for Ae.aegypti control,starting in 2008.Initial research focused on Ae.aegypti mating behavior and sterilization methods,followed by successful laboratory and semi-field trials that demonstrated population suppression.The first open-field trial in 2020 confirmed the eff-cacy of the SIT in reducing Ae.aegypti populations under real-world conditions.Currently,the research is in a phase involving a cluster-randomized superiority-controlled trial.This planned trial will compare the standard vector control program with the same program augmented by the SIT,aiming to assess the impact of the SIT on dengue incidence as the primary outcome.Implementing robust epidemiological trials to evaluate the effectiveness of the SiT is com-plex due to potential spillover effects from mosquito and human movement across study areas.Additionally,con-ducting the SIT requires significant development and operational investments.Despite these challenges,the ongo-ing Cuban trial holds promise for establishing the SIT as an effective and sustainable tool for Ae.aegypti control and for reducing the burden of mosquito-borne dise

关 键 词：CUBA Aedes aegypti Sterile insect technique Vector control Arbovirus transmission MOSQUITO 

分 类 号：R184.31[医药卫生—流行病学]