Foxc1b regulates brain pericyte proliferation in zebrafish larvae  

作　　者：Huaxing Zi Xiaolan Peng Le Sun Hongyu Li Xiulian Shen Minjia Chen Qiusui Deng Ye Hua Jiulin Du Jia Li 

机构地区：[1]Institute of Neuroscience,State Key Laboratory of Neuroscience,CAS Center for Excellence in Brain Science and Intelligence Technology,Chinese Academy of Sciences,Shanghai 200031,China [2]Dongguan Innovation Institute,Guangdong Medical University,Dongguan,Guangdong 523808,China [3]University of Chinese Academy of Sciences,Beijing 100049,China [4]School of Life Science and Technology,ShanghaiTech University,Shanghai 200031,China

出　　处：《Journal of Genetics and Genomics》2024年第11期1334-1337,共4页遗传学报（英文版）

基　　金：supported by the National Key R&D Program of China(2019YFA0801603 to J.L.);National Natural Science Foundation of China(31701265 to X.P.);Shanghai Natural Science Foundation(22ZR1469700 to J.L.);SA-SIBS Scholarship Program(to J.L.);Youth Innovation Promotion Association of Chinese Academy of Sciences(to J.L.)。

摘　　要：Pericytes,the mural cells enveloping small vessels,play a crucial role in maintaining the integrity of the blood-brain barrier(BBB)(Armulik et al.,2010;Daneman et al.,2010).Their loss leads to significant defects in BBB function,characterized by increased transcytosis across endothelial cells(ECs),diminished deposition of the cerebrovascular basement membrane,and compromised differentiation of astrocyte end-feet(Armulik et al.,2010;Daneman et al.,2010).

关 键 词：cytes BASEMENT 

分 类 号：Q421[生物学—神经生物学]