从“相火理论”辨治糖皮质激素性骨质疏松症  

Differentiation and treatment of glucocorticoid-induced osteoporosis from the theory of “phase fire”

作　　者：吴俊 李勇[2] 徐睿[2] WU Jun;LI Yong;XU Rui(Graduate School of Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;Second Department of Orthopaedics,Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanchang 330006,China)

机构地区：[1]江西中医药大学研究生院,江西南昌330004 [2]江西中医药大学附属医院骨二科,江西南昌330006

出　　处：《中国骨质疏松杂志》2024年第12期1863-1866,共4页Chinese Journal of Osteoporosis

基　　金：国家自然科学基金(82305279);江西省中医药管理局科技计划(2023A0219)。

摘　　要：以“相火理论”为指导,探析糖皮质激素性骨质疏松症(glucocorticoid-induced osteoporosis, GIOP)的病机及诊治,认为超量激素损害机体,引起相火妄动,致使机体阴阳失调,化髓成骨功能失常,产生GIOP。相火妄动为GIOP发生的根本病机。辨治当以平复相火为根本,以调整阴阳为纲要,治宜壮水之主,滋阴填精,以左归丸补之,或引火归元,温阳益气,以金匮肾气丸补之。基于“相火理论”辨治GIOP具有独特的应用价值,值得进行深入探讨,以期为临床防治GIOP提供新的思路。The pathogenesis,diagnosis,and treatment of glucocorticoid-induced osteoporosis were analyzed under the guidance of the"phase fire theory".It was concluded that excessive hormone levels damage the body,leading to wild movement of phase fire and result ing in an imbalance of Yin and Yang,dysfunction of marrow osteogenesis,and the development of GIOP.The fundamental pathogenesis of GIOP is related to the overreaction of fire.Treatment should be based on regulating the phase fire,adjusting Yin and Yang as a framework,strengthening water as the main focus,nourishing Yin and replenishing essence,supplementing Zuo-Gui Pills or returning phase fire to reduce excess fire energy,while warming Yang energy and supplementing Jin-Gui-Shen-Qi Pills.Differentiating and treating GIOP based on the theory of"phase fire"has unique practical value and deserves further discussion in order to provide new insights for clinical prevention and treatment of GIOP.

关 键 词：相火理论 糖皮质激素性骨质疏松 中医药 病机 治法 

分 类 号：R259[医药卫生—中西医结合]