Generation of biaxially accelerating static Airy light-sheets with 3D-printed freeform micro-optics  

作　　者：Yanis Taege Tim Samuel Winter Sophia Laura Schulz Bernhard Messerschmidt Ça˘glar Ataman 

机构地区：[1]University of Freiburg,Department of Microsystems Engineering,Laboratory for Micro-Optics,Freiburg,Germany [2]GRINTECH GmbH,Jena,Germany [3]University of Freiburg,Department of Microsystems Engineering,Microsystems for Biomedical Imaging Laboratory,Freiburg,Germany

出　　处：《Advanced Photonics Nexus》2023年第5期72-80,共9页先进光子学通讯（英文）

基　　金：This project has received funding from the European Union’s Horizon 2020 Research and Innovation Program under Grant Agreement No.871212.

摘　　要：One-dimensional Airy beams allow the generation of thin light-sheets without scanning,simplifying the complex optical arrangements of light-sheet microscopes(LSMs)with an extended field of view(FOV).However,their uniaxial acceleration limits the maximum numerical aperture of the detection objective in order to keep both the active and inactive axes within the depth of field.This problem is particularly pronounced in miniaturized LSM implementations,such as those for endomicroscopy or multi-photon neural imaging in freely moving animals using head-mounted miniscopes.We propose a new method to generate a static Airy light-sheet with biaxial acceleration,based on a novel phase profile.This light-sheet has the geometry of a spherical shell whose radius of curvature can be designed to match the field curvature of the micro-objective.We present an analytical model for the analysis of the light-sheet parameters and verify it by numerical simulations in the paraxial regime.We also discuss a micro-optical experimental implementation combining gradient-index optics with a 3D-nanoprinted,fully refractive phase plate.The results confirm that we are able to match detection curvatures with radii in the range of 1.5 to 2 mm.

关 键 词：light-sheet microscopy Airy beam accelerating beams field curvature two-photon polymerization 

分 类 号：O43[机械工程—光学工程]