不同浓度对比剂和注射速率在锥光束乳腺CT中的应用比较  

Comparison of cone-beam breast CT with different concentrations and injection speeds

作　　者：周春妍 何浩强[1] 何妮[1] 伍尧泮[1] ZHOU Chunyan;HE Haoqiang;HE Ni;WU Yaopan(Department of Medical Imaging,Sun Yat-Sen University Cancer Center,State Key Laboratory of Oncology in South China,Guangdong Provincial Clinical Research Center for Cancer,Guangzhou 510060,China)

机构地区：[1]中山大学肿瘤防治中心影像科、华南恶性肿瘤防治全国重点实验室、广东省恶性肿瘤临床医学研究中心,广东广州510060

出　　处：《医学影像学杂志》2024年第11期62-65,共4页Journal of Medical Imaging

基　　金：国家重点研发计划课题项目(国家重点新产品计划)(编号:2017YFC0112605)。

摘　　要：目的分析碘对比剂浓度和注射速率对锥光束乳腺CT增强扫描(CE-CBBCT)病灶强化的影响,以期探讨较为理想的对比剂注射方案。方法选取中山大学肿瘤防治中心358例临床诊断为乳腺癌的患者,均行CE-CBBCT。根据增强扫描所用碘对比剂浓度(370 mgI/ml,350 mgI/ml)不同分为370组186例和350组172例,观察病灶的强化效果。结果静脉注射对比剂2 min病灶的强化CT值>1 min病灶的强化CT值,差异有统计学意义(P<0.05)。相同的注射速率,370组和350组病灶的强化比较,差异无统计学意义(P>0.05)。350组和370组随着注射速率的增加,病灶强化逐渐增加,370组病灶强化CT值差异无统计学意义(P>0.05),350组病灶强化CT值差异有统计学意义(P<0.05)。结论2 min病灶的强化CT值优于1 min。相同注射速率,350组对比剂病灶强化CT值和370组比较差异无统计学意义(P>0.05)。使用370 mgI/ml对比剂可适当降低注射速率,使用350 mgI/ml对比剂可适当加快注射速率。Objective To evaluate the effect of different concentration and injection flow rate of iodine contrast agent on the enhancement of CE-CBBCT lesions,in order to explore an ideal contrast agent injection scheme.Methods A total of 358 patients with clinical diagnosis of breast cancer in Sun Yat-Sen University Cancer Center were collected,and all patients underwent enhanced breast CT scans.The patients were divided into 370 group and 350 group according to the concentration of contrast agent(370 mgI/ml,350 mgI/ml)used in enhanced scanning,and the enhancement effect of lesions was observed.Results The enhanced CT value of the lesion at 2 min after intravenous injection of contrast agent was greater than the enhanced CT value of the lesion at 1 min,and the difference was statistically significant(P<0.05).At the same injection speed,there was no significant difference in the enhancement of lesions between the 370 and 350 group(P>0.05).With the increase of injection speed,the enhancement of lesions in the 350 group and the 370 group gradually increased.There was no significant difference in the CT value of the lesion in the 370 group(P>0.05),and the difference in the enhanced CT value of the lesion in the 350 group was statistically significant(P<0.05).Conclusion The enhanced CT value of 2 min lesions is better than 1 min.At the same injection speed,the contrast-enhanced CT value of the 350 group is the same as that of the 370 group.The use of 370 contrast agent can appropriately reduce the injection speed,and the use of 350 contrast agent can appropriately speed up the injection speed.

关 键 词：乳腺癌 对比剂浓度 注射速率 锥光束 体层摄影术 X线计算机 

分 类 号：R981[医药卫生—药品] R814.42[医药卫生—药学]