PCOS患者卵巢形态学、血流参数与FAI关系及疗效预测效能  

The relationship between ovarian morphology,blood flow parameters,and FAI in patients with PCOS and the predic⁃tive efficacy of treatment

作　　者：张坤 ZHANG Kun(Department of Functional Examination,Chinese Academy of Traditional Chinese Medicine Guang'anmen Hospital Baoding Hospital,Baoding 071000,China)

机构地区：[1]中国中医科学院广安门医院保定医院功能检查科,河北保定071000

出　　处：《医学影像学杂志》2024年第11期127-131,共5页Journal of Medical Imaging

基　　金：河北省保定市科技计划项目(编号:2341ZF114)。

摘　　要：目的探究多囊卵巢综合征(PCOS)患者卵巢形态学、血流参数与游离睾酮指数(FAI)关系及疗效预测效能。方法选取我院收治的70例PCOS患者作为观察对象,统计卵巢血流参数指标:收缩期峰值血流速度(PSV)、舒张末期血流速度(EDV)、阻力指数(RI);形态学指标:平均卵巢体积(MOV)、较大卵巢体积(MaxOV)、平均卵泡数目(MFN)。Spearman分析其与FAI相关性,同时给予PCOS患者促排卵药物治疗,根据促排卵疗效分为成功组和失败组,比较两组卵巢形态学、血流参数指标,绘制受试者工作特征曲线(ROC)、决策曲线(DCA)分析疗效预测效能。结果MOV、MaxOV、MFN、PSV、EDV比较:FAI>20者>FAI 10~20者>FAI 5~10者,差异有统计学意义(P<0.05);RI比较:FAI>20者<FAI 10~20者<FAI 5~10者,差异有统计学意义(P<0.05);PCOS患者FAI与EDV、MOV、PSV、MaxOV、MFN呈正相关,与RI呈负相关(P<0.05);成功组MOV、MaxOV、MFN、PSV、EDV低于失败组,RI高于失败组,差异有统计学意义(P<0.05);Logistic回归显示,MOV、MaxOV、MFN、PSV、EDV、RI是PCOS患者促排卵失败影响因素(P<0.05);ROC曲线和DCA曲线显示,卵巢形态学、血流参数联合预测PCOS患者促排卵疗效具有一定参考价值和临床效用。结论PCOS患者卵巢形态学、血流参数与FAI密切相关,联合检测有助于提高促排卵疗效预测效能,具有一定临床适用性。Objective To investigate the relationship between ovarian morphology,blood flow parameters,and free androgen index(FAI)in patients with polycystic ovary syndrome(PCOS),as well as the predictive efficacy of treatment.Meth⁃ods A total of 70 patients with PCOS admitted to our hospital were selected as the research subjects.The ovarian blood flow parameters in terms of systolic peak velocity(PSV),end diastolic velocity(EDV),resistance index(RI)and morphological parameters of mean ovarian volume(MOV),and maximum ovarian volume(MaxOV),mean follicle number(MFN)were statistically analyzed.Spearman analysis was conducted to investigate their correlation with FAI.At the same time,the patients with PCOS were treated with ovulation-stimulating drugs,and divided into success group and failure group according to the efficacy of ovulation induction.The ovarian morphology and blood flow parameters were compared between the two groups,and the receiver operating characteristic(ROC)and decision curve(DCA)were used to analyze the efficacy prediction performance.Results As for the comparison of MOV,MaxOV,MFN,PSV,and EDV,those with FAI greater than 20 were greater than those with FAI 10~20,which were greater than those with FAI 5~10(P<0.05);For the comparison of RI,those with FAI greater than 20 were less than those with FAI 10~20,which were less than those with FAI 5~10(P<0.05);FAI in patients with PCOS was positively correlated with EDV,MOV,PSV,MaxOV,and MFN,and negatively correlated with RI(P<0.05);in the success group,MOV,MaxOV,MFN,PSV,EDV were lower than those in the failure group,and RI was higher than that in the failure group(P<0.05);logistic regression showed that MOV,MaxOV,MFN,PSV,EDV,and RI were factors affecting the failure of ovarian stimulation in patients with PCOS(P<0.05);ROC curve and DCA curve showed that ovarian morphology and blood flow parameters combined to predict the efficacy of ovarian stimulation in patients with PCOS had certain value reference and clinical utility.Conclusion The morphology and blood flow

关 键 词：多囊卵巢综合征 卵巢形态学 血流参数 游离睾酮指数 超声检查 

分 类 号：R711.75[医药卫生—妇产科学] R445.1[医药卫生—临床医学]