电针治疗慢性阻塞性肺疾病稳定期骨骼肌萎缩患者的临床观察  

Clinical Observation of Electroacupuncture Treating Patients with Skeletal Muscle Atrophy in Stable Stage of Chronic Obstructive Pulmonary Disease

作　　者：颜莹 曾扬[1] 刘震 易思程 邓雨寒 张葵[1] YAN Ying;ZENG Yang;LlU Zhen;Yl Sicheng;DENG Yuhan;ZHANG Kui(Guizhou Provincial Peoples Hospital,Guiyang 550002,Guizhou,China)

机构地区：[1]贵州省人民医院,贵州贵阳550002

出　　处：《中华中医药学刊》2024年第12期142-145,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81960892);贵州省中医药管理局项目(黔中医药发〔2021〕040号)。

摘　　要：目的观察电针治疗慢性阻塞性肺疾病(COPD)稳定期骨骼肌萎缩患者的疗效及安全性,为COPD骨骼肌萎缩治疗提供思路。方法采用随机对照临床试验设计,选取贵州省人民医院和贵州中医药大学第一附属医院就诊的120例COPD3级患者,且中医辨证为肺脾肾虚证,随机分配为两组,每组分别60例。对照组采用西医常规治疗。治疗组采用西医常规治疗+电针治疗,针刺1次/d,5d为1个疗程,每疗程后间隔2d,共8个疗程。观察治疗前后中医临床症状积分、CAT评分、骨骼肌萎缩指标、股直肌横截面积、肌力、Barthel指数及血常规、肝肾功能的变化。结果治疗后,治疗组中医症候积分、CAT评分较对照组降低(P<0.05);治疗组骨骼肌萎缩指标、股直肌横截面积、肌力、Barthel指数较对照组上升(P<0.05)。患者安全性指标治疗前后差异无统计学意义。结论电针治疗能改善COPD稳定期骨骼肌萎缩患者的中医临床症状,延缓骨骼肌萎缩,提高生活质量,且安全性良好,可应用于临床。Objective This study observed the efficacy and safety of electroacupuncture in the treatment of skeletal muscle atrophy in patients with chronic obstructive pulmonary disease(COPD)in the stable phase and provided ideas for the treatment.Methods It was a randomized controlled trial.The study included 120 patients with COPD in stable stage 3 who were deficiency of lung,spleen and kidney in TCM syndrome differentiation.The patients were randomized into two groups and there were 60 patients in each group.The control group received conventional western medicine treatment,and the treatment group received conventional western medicine treatment and electroacupuncture treatment,which needled once a day,5 days as a course of treatment,a total of 8 courses of treatment.The interval between each treatment course was 2 days.The changes of TCM clinical symptom scores,COPD Assessment Test(CAT)scores,skeletal muscle atrophy index,muscle strength,cross-sectional area of rectus femoris,Barthel index,blood routine,liver and kidney function before and after treatment were observed.Results After treatment,TCM symptom score and CAT score in the treatment group were reduced compared to those of the control group(P<005).The indexes of skeletal muscle atrophy,cross-sectional area of rectus femoris and muscle strength and Barthel index in the treatment group were increased compared to the control group(P<005).Before and after treatment,there was no statistical difference in safety indexes.Conclusion Electroacupuncture can improve the clinical symptoms,delay skeletal muscle atrophy and improve the quality of life of the stable COPD patients with skeletal muscle atrophy.It is safety and can be used in clinic.

关 键 词：慢性阻塞性肺疾病 稳定期 骨骼肌萎缩 肺脾肾虚证 电针 随机对照试验 

分 类 号：R245.31[医药卫生—针灸推拿学]