栀子豉汤结合宁神补肾法针刺治疗失眠(心肾不交型)临床效果研究  

Clinical Effect of Zhizichi Decoction(栀子豉汤)Combined with Calming Mind and Tonifying Kidney Acupuncture on insomnia(Heart-Kidney Disharmony Type)

作　　者：潘英英 康静[1] 王海铭[1] PAN Yingying;KANG Jing;WANG Haiming(Shanxi Provincial People$Hospital,Taiyuan 030012,Shanxi,China)

机构地区：[1]山西省人民医院,山西太原030012

出　　处：《中华中医药学刊》2024年第12期224-227,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：山西省中医药管理局科研项目(2022ZYYC068)。

摘　　要：目的观察栀子豉汤结合宁神补肾法针刺治疗失眠(心肾不交型)临床效果。方法将山西省人民医院中医科2021年2月—2023年3月收治的110例失眠(心肾不交型)患者以随机数字表法分为对照组、观察组,各组55例,给予对照组患者右佐匹克隆片治疗,观察组患者口服右佐匹克隆片同时结合栀子豉汤及宁神补肾法针刺治疗,治疗及研究过程中;对照组脱落2例患者,观察组脱落3例患者,比较各组数据:疗效、患者中医症候积分(入睡困难、心烦失眠、心悸多梦、潮热盗汗、五心烦热、头晕耳鸣等)变化、多导睡眠监测(Polysomnography,PSG)指标变化、焦虑自评(Self-Rating Anx-iety Scale,SAS)及抑郁自评量表(Self-rating depression scale,SDS)评分变化、匹兹堡睡眠指数(Pittsburgh sleep quality in-dex,PSQI)评分变化及简易智力状态检查量表(Mini-mental State Examination,MMSE)评分变化、生活质量量表(short-form36questionnaire,SF-36)评分变化、不良反应情况。结果观察组与对照组患者治疗总有效率分别为96.15%、83.02%,观察组治疗总有效率显著更高(P<0.05)。治疗前两组患者中医症候积分(入睡困难、心烦失眠、心悸多梦、潮热盗汗、五心烦热、头晕耳鸣等)、PSG相关指标(睡眠总时长、觉醒时长、睡眠潜伏期与睡眠效率)、SAS评分以及SDS评分、PSQI评分、MMSE评分以及SF-36评分比较(P>0.05),经治疗后各组患者中医症候积分(入睡困难、心烦失眠、心悸多梦、潮热盗汗、五心烦热、头晕耳鸣等)、PSG相关指标(睡眠总时长、觉醒时长、睡眠潜伏期与睡眠效率)、SAS评分以及SDS评分、PSQI评分、MMSE评分以及SF-36评分均显著改善,观察组患者治疗后中医症候积分(入睡困难、心烦失眠、心悸多梦、潮热盗汗、五心烦热、头晕耳鸣等)、PSG相关指标(睡眠总时长、觉醒时长、睡眠潜伏期与睡眠效率)、SAS评分以及SDS评分、PSQI评分、MMSE评分以及Objective To observe the clinical effect of Zhizichi Decoction(栀子豉汤)combined with calming mind and tonify-ing kidney acupuncture on insomnia(heart-kidney disharmony type).Methods A total of 110 patients with insomnia(heart-kidney disharmony type)admitted to the Department of Traditional Chinese Medicine of Shanxi People's Hospital from February 2021 to March 2023 were divided into control group and observation group by random number table method,with 55 cases in each group.The patients in the control group were treated with dexzopicron tablet,and those in the observation group were treated with dexzopicron tablet combined with Zhizichi Decoction and calming mind and tonifying kidney acupuncture.During the treatment,2 patients fell off in the control group and 3 patients fell off in the observation group.The data of each group was compared,inclu-ding efficacy,TCM symptom scores(difficulty falling asleep,restlessness and insomnia,palpitations and dreams,hot flashes and night sweats,five heart restlessness,dizziness and tinnitus,etc),polysomnography(PSG)indicators,the scores of self-rating anxiety scale(SAS),self-rating depression scale(SDS),Pittsburgh sleep quality index(PSQI),mini-mental state examination(MMSE)and short form 36 questionnaire(SF-36),and adverse reactions.Results The total effective rates of the observation group and the control group were 96.15%and 83.02%,respectively,and the total effective rate of observation group was signifi-cantly higher(P<005).Before treatment,TCM syndrome scores(difficulty falling asleep,restlessness and insomnia,palpitations and dreams,hot flashes and night sweats,five heart restlessness,dizziness and tinnitus,etc),PSG related indicators(total sleep duration,wake duration,sleep latency and sleep efficiency),SAS score,SDS score,PSQI score,MMSE score and SF-36 score were not significant between the two groups(P>005).After treatment,TCM syndrome score(difficulty falling asleep,upset in-somnia,palpitation and multiple dreams,hot flash and night sweat,five upset fever,di

关 键 词：失眠 心肾不交型 栀子豉汤 宁神补肾法针刺 疗效 睡眠质量 不良反应 

分 类 号：R245.31[医药卫生—针灸推拿学]