基于因子分析和聚类分析的380例急性喘息性支气管炎患儿中医证候研究  

Study on traditional Chinese medicine syndromes of 380 children with acute asthmatic bronchitis based on factor analysis and cluster analysis

作　　者：王佩瑶 叶慧诗 冯杏珍 谢树斌 罗桂平 蔡艾媛 许柏华 WANG Peiyao;YE Huishi;FENG Xingzhen;XIE Shubin;LUO Guiping;CAI Aiyuan;XU Baihua(Department of Pediatrics,Dongguan Traditional Chinese Medicine Hospital,Guangdong Province,Dongguan523000,China;Graduate School,Guangzhou University of Chinese Medicine,Guangdong Province,Guangzhou510006,China)

机构地区：[1]广东省东莞市中医院儿科,广东东莞523000 [2]广州中医药大学研究生院,广东广州510006

出　　处：《中国医药导报》2024年第33期105-109,共5页China Medical Herald

基　　金：广东省中医药局中医药科研项目(20241347);广东省“十三五”中医重点专科奖励(儿科)(21000003);广东省东莞市社会科技发展项目(20221800900261);广东省许尤佳名医传承工作室。

摘　　要：目的通过因子分析和聚类分析研究儿童急性喘息性支气管炎(AB)的证候分布模式和特征,为临床辨证提供依据,推动AB患儿证候标准化研究。方法采集广东省东莞市中医院2022年2月至2024年2月儿科住院部及门诊380例AB患儿的中医证候信息,计算中医证候的频数,排除低频数的中医证候信息纳入因子分析模型,提取公因子作为变量进行系统聚类分析。结果聚类分析共提取了9个公因子,累计贡献率为65.746%。其中第1类包含公因子F2、F4,第2类包含公因子F8、F9,第3类包含公因子F3、F6,第4类包含公因子F1、F5。结论AB患儿的证候表现与主要与常见4类证型有关,即痰热闭肺证、风热闭肺证、湿热闭肺证和毒热闭肺证,其中以热象为主要表现。Objective To explore the distribution pattern and characteristics of acute asthmatic bronchitis(AB)symptoms in children by factor analysis combined with cluster analysis and to provide a basis for clinical diagnosis,and to promote standardized research on AB symptoms in children.Methods The information on tradition Chinese medicine evidence of 380 children with AB in the Pediatric Inpatient Department and Outpatient Clinic of Dongguan Traditional Chinese Medicine Hospital,Guangdong Province from February 2022 to February 2024 was selected,and the frequency counts of traditional Chinese medicine evidence were calculated,and those with low frequencies were excluded from being included in the factor analysis model,and the common factors were extracted as the variables for the systematic cluster analysis.Results A total of nine common factors were extracted by cluster analysis,and the cumulative contribution rate was 65.746%.The first category contains common factors F2 and F4,the second category contains common factors F8 and F9,the third category contains common factors F3 and F6,and the fourth category contains common factors F1 and F5.Conclusion In summary,the symptoms of AB in children are associated with four primary syndrome types:wind-heat blocking lung syndrome,phlegm-heat blocking lung syndrome,damp-heat blocking lung syndrome,and toxin-heat blocking lung syndrome.The majority of these symptoms are indicative of heat.

关 键 词：急性喘息性支气管炎 中医证候 因子分析 聚类分析 儿童 

分 类 号：R725.6[医药卫生—儿科]