间隙和持续蓝光照射治疗新生儿黄疸的临床效果观察  

Observation on clinical effect of intermittent and continuous blue light irradiation the treatment of neonatal jaundice

作　　者：黄婷蓉 HUANG Ting-rong(Department of Pediatrics,Quanzhou Guangqian Hospital,Quanzhou 362300,China)

机构地区：[1]泉州市光前医院儿科,362300

出　　处：《中国现代药物应用》2024年第22期76-78,共3页Chinese Journal of Modern Drug Application

摘　　要：目的 比较间隙蓝光照射与持续蓝光照射在新生儿黄疸治疗中的临床效果及安全性。方法 92例新生儿黄疸患儿,采取随机数表法将所有患儿分为观察组和对照组,每组46例。对照组行持续蓝光照射治疗,观察组行间隙蓝光照射治疗。比较两组临床疗效、总胆红素水平、临床指标、不良反应发生情况。结果 观察组和对照组的总有效率比较,差异无统计学意义(P>0.05)。治疗1、2、3 d,观察组的总胆红素水平分别为(165.58±10.24)、(152.56±8.59)、(100.52±7.64)μmol/L,均显著低于对照组的(190.96±10.48)、(168.84±8.52)、(117.48±6.59)μmol/L,差异有统计学意义(P<0.05)。观察组的黄疸症状消退时间(4.52±1.03)d短于对照组的(6.85±1.08)d,熟睡时间(18.59±1.03)h/d长于对照组的(15.54±1.74)h/d,哭闹频率(3.56±0.38)次/d少于对照组的(5.25±0.84)次/d,差异有统计学意义(P<0.05)。观察组的不良反应发生率2.17%低于对照组的13.04%,差异有统计学意义(P<0.05)。结论 在新生儿黄疸的临床治疗中,持续和间隙蓝光照射均可以获得较好效果,但相比较而言,采取间隙蓝光照射治疗能够在降低总胆红素水平的基础上保障治疗的安全性,减少患儿的啼哭频率,保证其睡眠充足,故值得推广。Objective To compare the clinical effect and safety of intermittent and continuous blue light irradiation the treatment of neonatal jaundice.Methods 92 cases of neonatal jaundice were divided into an observation group and a control group by random number table method,with 46 cases in each group.The control group received continuous blue light irradiation,and the observation group received intermittent blue light irradiation.The clinical efficacy,total bilirubin level,clinical indicators and adverse reactions were compared between the two groups.Results There was no significant difference in total effective rate between the observation group and the control group(P>0.05).After 1,2 and 3 d of treatment,the total bilirubin levels in the observation group were(165.58±10.24),(152.56±8.59) and(100.52±7.64) μmol/L,which were significantly lower than(190.96±10.48),(168.84±8.52) and(117.48±6.59) μmol/L in the control group,and the difference was statistically significant(P<0.05).In the observation group,the disappearance time of jaundice symptoms was(4.52±1.03) d,which was shorter than(6.85±1.08) d in the control group;the sleeping time was(18.59±1.03) h/d,which was longer than(15.54±1.74) h/d in the control group;the frequency of crying was(3.56±0.38)/d,which was less than(5.25±0.84)/d in the control group;the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 2.17%,which was lower than 13.04% in the control group,and the difference was statistically significant(P<0.05).Conclusion In the clinical treatment of neonatal jaundice,both continuous and intermittent blue light irradiation can achieve better results,but in comparison,intermittent blue light irradiation can guarantee the safety of the treatment based on the reduction of the total bilirubin level,reduce the frequency of crying of the children,and ensure adequate sleep,so it is worth promoting.

关 键 词：间隙蓝光照射 持续蓝光照射 新生儿黄疸 临床疗效 总胆红素 

分 类 号：R722.17[医药卫生—儿科]