骨吸收抑制剂治疗骨质疏松的效果评价  

Evaluation of the effect of bone resorption inhibitors in the treatment of osteoporosis

作　　者：肖淑芳 蒋先奉 XIAO Shu-fang;JIANG Xian-feng(Hukou County Traditional Chinese Medicine Hospital,Jiujiang 332500,China)

机构地区：[1]湖口县中医医院,332500

出　　处：《中国实用医药》2024年第22期115-118,共4页China Practical Medicine

摘　　要：目的 探讨骨质疏松患者采用骨吸收抑制剂治疗的效果。方法 选取60例骨质疏松患者,随机分为观察组(采用碳酸钙D3片+伊班膦酸钠注射液治疗)和对照组(采用碳酸钙D3片治疗),各30例。比较两组骨密度、康复指标[Oswestry功能障碍指数问卷表(ODI)、视觉模拟评分法(VAS)、Morse跌倒风险评估量表(MFS)、Berg平衡量表(BSS)评分及步行6 m所需时间]、生活质量。结果 治疗后,观察组腰椎、髋部骨密度大于对照组(P<0.05)。治疗后,观察组ODI评分为(31.01±2.60)分、BSS评分为(54.61±3.17)分、步行6 m所需时间为(7.95±0.64)s、MFS评分为(40.24±2.17)分、VAS评分为(2.85±0.44)分,对照组ODI评分为(37.68±5.47)分、BSS评分为(49.24±8.44)分、步行6 m所需时间为(8.96±0.77)s、MFS评分为(45.20±6.77)分、VAS评分为(3.19±0.65)分。治疗后,观察组ODI评分、MFS评分、VAS评分低于对照组,BSS评分高于对照组,步行6 m所需时间短于对照组(P<0.05)。治疗后,观察组社会功能、情感职能、生理职能、活力状况评分均高于对照组(P<0.05)。结论 骨吸收抑制剂治疗骨质疏松可有效改善骨密度,提升疗效,临床应用价值较高。Objective To explore the effect of bone resorption inhibitors in the treatment of osteoporosis.Methods 60 patients with OP were randomly divided into an observation group(calcium carbonate D3 tablets +sodium ibandronate injection) and a control group(calcium carbonate D3 tablets),each with 30 cases.Both groups were compared in terms of bone mineral density,rehabilitation indicators [scores of Oswestry Disability Index(ODI),Visual Analogue Scale(VAS),Morse Fall Scale(MFS) and Berg Balance Scale(BSS),time required to walk 6 m] and quality of life.Results After treatment,the bone density of lumbar spine and hip in the observation group was greater than that of the control group(P<0.05).After treatment,the ODI score in the observation group was(31.01±2.60) points,the BSS score was(54.61±3.17) points,the time required to walk 6 m was(7.95±0.64) s,the MFS score was(40.24±2.17) points,and the VAS score was(2.85±0.44) points;in the control group,the ODI score was(37.68±5.47) points,the BSS score was(49.24±8.44) points,the time required to walk 6 m was(8.96±0.77) s,the MFS score was(45.20±6.77) points,and the VAS score was(3.19±0.65) points.After treatment,the ODI score,MFS score,and VAS score of the observation group were lower than those of the control group,the BSS score was higher than that of the control group,and the time required to walk 6 m was shorter than that of the control group(P<0.05).After treatment,the scores of social functioning,role-emotional,role-physical,and vitality of the observation group were higher than those of the control group(P<0.05).Conclusion Bone resorption inhibitors can effectively improve bone density and enhance efficacy in the treatment of steoporosis,with high clinical application value.

关 键 词：骨质疏松 骨吸收抑制剂 骨密度 康复指标 生活质量 

分 类 号：R259[医药卫生—中西医结合]