丙泊酚与瑞芬太尼复合麻醉在结肠癌手术中对患者生命体征、应激及免疫功能的影响分析  

Analysis of the Effects of Propofol and Remifentanil Combined Anesthesia on Vital Signs,Stress and Immune Function in Patients Undergoing Colon Cancer Surgery

作　　者：赵树郁 包玉龙 ZHAO Shuyu;BAO Yulong(College of Basic Medicine,Inner Mongolia Medical University,Hohhot,Inner Mongolia Autonomous Region,010110,China;Department of Anesthesia,Baotou Cancer Hospital,Baotou,Inner Mongolia Autonomous Region,014000,China)

机构地区：[1]内蒙古医科大学基础医学院,内蒙古呼和浩特010110 [2]包头市肿瘤医院麻醉科,内蒙古包头014000

出　　处：《中外医疗》2024年第31期96-100,共5页China & Foreign Medical Treatment

摘　　要：目的探讨丙泊酚与瑞芬太尼复合麻醉在结肠癌手术中对患者生命体征、应激反应及免疫功能的影响。方法回顾性选取2021年1月—2023年12月于包头市肿瘤医院接受手术治疗的80例结肠癌患者的临床资料,根据患者接受的麻醉方式不同,分为常规组和探究组,每组40例。常规组应用七氟烷复合丙泊酚静吸复合麻醉,探究组采用丙泊酚与瑞芬太尼复合麻醉。对比两组的生命体征、应激水平、免疫功能和不良反应发生情况。结果麻醉后,探究组生命体征水平较常规组更稳定,应激水平、免疫功能均优于常规组,差异有统计学意义(P均<0.05)。探究组不良反应发生率为7.50%(3/40)低于常规组的25.00%(10/40),差异有统计学意义(χ2=4.501,P<0.05)。结论丙泊酚与瑞芬太尼复合麻醉在结肠癌手术中应用,能够更有效地稳定患者的生命体征,降低应激反应,并且对免疫功能的负面影响更小,同时减少了不良反应的发生率。Objective To investigate the effects of propofol and remifentanil combined anesthesia on vital signs,stress response and immune function in patients undergoing colon cancer surgery.Methods The clinical data of 80 patients with colon cancer who underwent surgical treatment in Baotou Cancer Hospital from January 2021 to December 2023 were retrospectively selected.According to the different anesthesia methods received by the patients,they were divided into routine group and study group,with 40 cases in each group.The routine group was treated with sevoflurane combined with propofol intravenous inhalation anesthesia,and the study group was treated with propofol and remifentanil combined anesthesia.The vital signs,stress level,immune function and adverse reactions of the two groups were compared.Results After anesthesia,the vital signs of the study group were more stable than those of the routine group,and the stress level and immune function were better than those of the routine group(all P<0.05).The incidence of adverse reactions in the study group was 7.50%(3/40),which was lower than that in the routine group 25.00%(10/40),and the difference was statistically significant(χ2=4.501,P<0.05).Conclusion The application of propofol and remifentanil combined anesthesia in colon cancer surgery can more effectively stabilize the vital signs of patients,reduce stress response,and have less negative impact on immune function,and reduce the incidence of adverse reactions.

关 键 词：丙泊酚 瑞芬太尼 复合麻醉 结肠癌手术 生命体征 应激反应 免疫功能 

分 类 号：R4[医药卫生—临床医学]