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作 者:蒋欣烨 林思旸 陈静怡 黄晓铭[2,4,5,6] 林文雯 袁音 黄峰[1,2,3,4,5,6] JIANG Xinye;LIN Siyang;CHEN Jingyi;HUANG Xiaoming;LIN Wenwen;YUAN Yin;HUANG Feng(College of Integrative Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou 350001,China;Provincial Clinical College of Medicine,Fujian Medical University,Fuzhou 350001,China;Department of Geriatrics,Fujian Provincial Hospital,Fuzhou 350001,China;Fujian Provincial Institute of Clinical Geriatrics,Fuzhou 350001,China;Fujian Provincial Center of Geriatrics,Fuzhou 350001,China;Fujian Provincial Key Laboratory of Geriatrics,Fuzhou 350001,China)
机构地区:[1]福建中医药大学中西医结合学院,福州350001 [2]福建医科大学省立临床医学院,福州350001 [3]福建省立医院老年医学科,福州350001 [4]福建省临床老年病研究所,福州350001 [5]福建省老年医学中心,福州350001 [6]福建省老年病重点实验室,福州350001
出 处:《中国医药指南》2024年第36期6-8,共3页Guide of China Medicine
基 金:福建省卫健委重大科研专项项目(2022ZD01006)。
摘 要:目的本研究旨在探讨社区老年人群内在能力与衰弱之间的相关性。方法研究纳入2020—2021年福州市温泉社区卫生服务中心健康体检的2123名≥60岁老年人进行调查分析,采用Fried表型诊断衰弱,根据世界卫生组织(WHO)提出的认知、运动、感觉、活力及心理5个领域评估老年人的内在能力。应用单因素和多因素Logistic回归对内在能力与衰弱的相关性进行分析。结果2123名老年人中,衰弱227例(10.69%),低内在能力716例(33.73%)。多因素Logistic回归显示,调整混杂因素后,相比于高内在能力组,低内在能力组的衰弱风险为3.046倍(95%CI 2.204~4.211)。内在能力各领域中,认知受损(OR 1.517,95%CI 1.107~2.078)、运动受损(OR 4.556,95%CI 1.815~11.436)、感觉受损(OR 2.041,95%CI 1.385~3.006)、活力受损(OR 3.358,95%CI 2.438~4.625)和心理受损(OR 2.764,95%CI 1.819~4.201)均与衰弱风险呈正相关。结论本研究基于单因素和多因素Logistic回归的方法分析得到低内在能力与衰弱的正相关关系,提示老年人内在能力下降的早期识别对于健康老龄化具有重要的公共卫生意义。Objective This study aims to explore the relationship between intrinsic capacity and frailty in the community-dwelling elderly population.Methods A total of 2,123 elderly individuals aged 60 and above,who underwent health examinations at the Wenquan Community Health Service Center in Fuzhou from 2020 to 2021,were included for investigation and analysis.Frailty was diagnosed by Fried phenotype,and the intrinsic abilities of the elderly were evaluated according to the five domains of cognition,motor,sensory,vitality and psychological proposed by the World Health Organization(WHO).The correlation between intrinsic capacity and frailty was analyzed using univariate and multivariate Logistic regression.Results Among the 2,123 elderly participants,227(10.69%)were diagnosed with frailty,and 716(33.73%)had low intrinsic capacity.Multivariate Logistic regression showed that,after adjusting for confounding factors,the frailty risk in the low intrinsic capacity group was 3.046 times higher(95%CI 2.204-4.211)compared to the high intrinsic capacity group.Impairments in cognition(OR 1.517,95%CI 1.107-2.078),mobility(OR 4.556,95%CI 1.815-11.436),sensory(OR 2.041,95%CI 1.385-3.006),vitality(OR 3.358,95%CI 2.438-4.625),and psychological function(OR 2.764,95%CI 1.819-4.201)were all positively associated with an increased risk of frailty.Conclusions This study,using univariate and multivariate Logistic regression analyses,found a positive association between low intrinsic capacity and frailty.It is suggested that the early identification of the decline of intrinsic ability in the elderly has important public health significance for healthy aging.
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