妊娠合并梅毒感染孕妇发生不良妊娠结局的影响因素分析  

Analysis of Factors Influencing Adverse Pregnancy Outcomes in Pregnant Women with Syphilis Infection

作　　者：朱孟 ZHU Meng(Medical Department,Longyan People’s Hospital,Longyan 364000,China)

机构地区：[1]龙岩人民医院医务科,龙岩364000

出　　处：《中国医药指南》2024年第36期123-126,共4页Guide of China Medicine

摘　　要：目的探究妊娠合并梅毒感染孕妇发生不良妊娠结局的影响因素。方法回顾性分析龙岩人民医院2022年1月至2024年5月30例妊娠合并梅毒感染孕妇的临床资料,收集妊娠结局资料,统计不良妊娠结局发生率,分析妊娠不良结局的影响因素。结果30例妊娠合并梅毒感染孕妇中,不良妊娠结局发生率为16.67%(5/30),早产、低体重、死胎占比分别为40.00%、40.00%、20.00%;单因素分析结果显示,年龄、文化程度、婚姻状态、梅毒分期、是否接受规范治疗为妊娠合并梅毒感染孕妇发生不良妊娠结局的影响因素(P<0.05);Logistic回归分析结果显示,非在婚(OR 2.239,95%CI 1.233~3.468)、本次梅毒分期(OR 2.328,95%CI 1.559~4.204)、未接受规范化治疗(OR 1.988,95%CI 1.234~3.002)为妊娠合并梅毒感染孕妇发生不良妊娠结局危险因素,年龄(OR 0.493,95%CI 0.215~0.775)、文化程度(OR 0.536,95%CI 0.348~0.845)为妊娠合并梅毒感染孕妇发生不良妊娠结局保护因素(P<0.05)。结论年龄、文化程度、婚姻状态、梅毒分期、规范化治疗均会影响妊娠合并梅毒感染孕妇不良妊娠结局的发生,建议加强针对性干预及规范化治疗,以改善孕妇妊娠结局。Objective To explore the influencing factors of adverse pregnancy outcomes in pregnant women with syphilis infection.Methods The clinical data of 30 pregnant women infected with syphilis infection from January 2022 to May 2024 were retrospectively analyzed,the pregnancy outcome data were collected,the incidence of adverse pregnancy outcomes was counted,and the influencing factors of adverse pregnancy outcomes were analyzed.Results Of the 30 patients,The incidence of adverse pregnancy outcomes was 16.67%(5/30),The proportion of preterm birth,low body weight and stillbirth were 40.00%,40.00%and 20.00%,respectively;As shown by the univariate analysis,Age,educational level,marital status,syphilis stage,and standardized treatment were the factors affecting adverse pregnancy outcomes in pregnant women with syphilis infection(P<0.05).As shown by the Logistic regression analysis,Non marital status(OR 2.239,95%CI 1.233-3.468),current syphilis staging(OR 2.328,95%CI 1.559-4.204),and lack of standardized treatment(OR 1.988,95%CI 1.234-3.002)are risk factors for adverse pregnancy outcomes in pregnant women with syphilis infection.Age(OR 0.493,95%CI 0.215-0.775)and educational level(OR 0.536,95%CI 0.348-0.845)are protective factors for adverse pregnancy outcomes in pregnant women with syphilis infection(P<0.05).Conclusions Age,educational level,marital status,syphilis stage and standardized treatment will all affect the adverse pregnancy outcomes in pregnant women infected with syphilis infection.It is suggested to strengthen targeted intervention and standardized treatment to improve pregnancy outcomes in pregnant women.

关 键 词：梅毒感染 妊娠 不良妊娠结局 

分 类 号：R714.25[医药卫生—妇产科学] R759.15[医药卫生—临床医学]