心理护理路径在乳腺癌晚期患者首次化疗不良情绪中的应用  

Psychological Care Pathway in the Adverse Emotions of Advanced Breast Cancer Patients Undergoing Their First Chemotherapy Treatment

作　　者：陈姗姗 任中海[1] 李长生[1] Chen Shanshan;Ren Zhonghai;Li Changsheng(The Second Ward of Oncology Department,Nanyang Central Hospital,Nanyang,Henan,473000,China)

机构地区：[1]南阳市中心医院肿瘤内科二病区,河南南阳473000

出　　处：《黑龙江医学》2024年第23期2914-2916,2919,共4页Heilongjiang Medical Journal

基　　金：河南省科技计划发展项目(202102310408)。

摘　　要：目的:探索心理护理路径对乳腺癌晚期患者首次化疗中不良情绪的干预效果。方法:选取2021年3月—2023年3月南阳市中心医院收治的122例乳腺癌晚期患者作为研究对象,采用随机数表法将其分为对照组(61例)和观察组(61例)。所有患者均接受了依从性、焦虑自评量表(SAS)、抑郁自评量表(SDS)、心理弹性量表(CD-RISC)、安德森症状量表中文版(MDASI-C)以及炎症因子水平[白细胞介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)]的测评。结果:干预后,两组患者不良情绪均有显著改善,观察组较对照组SAS及SDS评分均明显降低,差异有统计学意义(t=7.05、12.54,P<0.05);干预后,两组患者心理弹性各维度评分有不同程度的提高,观察组明显优于对照组,差异有统计学意义(t=6.23、5.23、5.79,P<0.05);干预后,两组患者安德森症状评估量表评分均明显降低,观察组明显优于对照组,差异有统计学意义(t=28.33、19.03,P<0.05);干预后,两组患者血清炎症因子IL-6和TNFα水平均明显降低,观察组明显优于对照组,差异有统计学意义(t=17.74、3.40,P<0.05)。结论:心理护理路径在乳腺癌晚期患者首次化疗中可以有效减轻患者的焦虑、抑郁情绪,提高患者依从性,降低炎症水平,有助于提高患者的生活质量和化疗效果。Objective:To explore the efficacy of a psychological care pathway to intervene in adverse emotions in advanced breast cancer patients undergoing their first chemotherapy treatment.Methods:122 cases of advanced breast cancer patients admitted to Nanyang Central Hospital from March 2021 to March 2023 were used as the study subjects.They were divided into the control group(61 cases,receiving conventional care)and the observation group(61 cases,using the psychological care pathway)with random number table method.All patients were assessed for adherence,Self-Assessment Scale for Anxiety(SAS),Self-Depression Scale(SDS),Connor-Davidson resilience scale(CD-RISC),Chinese Version of M.D.Adersion Symptom Inventory(MDASI-C)and levels of inflammatory factors(interleukin IL-6 and tumor necrosis factor TNF-α)were measured.Results:After intervention,the adverse mood of patients in both groups was significantly improved,and SAS and SDS scores in the observation group were significantly lower than those in the control group,with statistically significant difference(t=7.05,12.54;P<0.05).After intervention,the scores of psychological resilience of the two groups were improved to different degrees,and the observation group was significantly better than the control group,with statistically significant difference(t=6.23,5.23,5.79;P<0.05).After intervention,the score of Anderson Symptom Assessment Scale was significantly decreased in both groups,and the observation group was significantly better than the control group,with statistically significant difference(t=28.33,19.03;P<0.05).After intervention,the levels of serum inflammatory cytokines IL-6 and TNF-αwere significantly decreased in both groups,and the observation group was significantly better than the control group,with statistically significant difference(t=17.74,3.40;P<0.05).Conclusion:Psychological care pathway in the first chemotherapy of advanced breast cancer patients can effectively reduce patients’anxiety and depression and improve their compliance,which can help to im

关 键 词：心理护理 乳腺癌 不良情绪 心理状态 

分 类 号：R47[医药卫生—护理学]