高毒力肺炎克雷伯菌感染的诊治进展  

Updates in Diagnosis and Treatment of High Virulent Klebsiella Pneumoniae Infection

作　　者：贺小旭[1] 李周平 刘音[1] 饶芝国[1] 薛晓艳[1] HE Xiao-xu;LI Zhou-ping;LIU Yin;RAO Zhi-guo;XUE Xiao-yan(Department of Critical Care Medicine,Aerospace Center Hospital,Beijing 100049,China)

机构地区：[1]航天中心医院重症医学科,北京100049

出　　处：《中国合理用药探索》2024年第11期73-77,共5页Chinese Journal of Rational Drug Use

摘　　要：近30年来,一种有着特殊临床特征的肺炎克雷伯菌群被发现,感染者多表现为多发的转移性脓肿。其最初是在东亚地区流行,而后蔓延至全世界,给人类健康造成巨大威胁。为了描述这种特殊的菌群,人们将其称为高毒力肺炎克雷伯菌,但如何精确定义仍是一个尚未解决的问题。高毒力肺炎克雷伯菌可能导致严重的感染性休克及多脏器功能衰竭,治疗包括强效的抗感染、脏器功能支持、积极的血糖控制及脓肿部位的穿刺引流等。本研究总结了近年来的相关文献报道,以期更好地认识高毒力肺炎克雷伯菌感染及其治疗效果。In the past 30 years,a Klebsiella pneumoniae strain associated with special clinical features has been identified.Infected patients usually present with multiple metastatic abscesses.It was initially prevalent in East Asia,and then spread to the world,causing a great threat to human health.To describe this particular strain,it has been termed hypervirulent Klebsiella pneumoniae,but how to accurately define it remains an unresolved question.Highly virulent Klebsiella pneumoniae may lead to severe septic shock and multiple organ failure.Treatment includes strong anti-infection,organ function support,active blood glucose control and puncture and drainage of abscess site.In this study,we summarized related literature in recent years,in order to better understand and treat the high virulent Klebsiella pneumoniae infection.

关 键 词：高毒力肺炎克雷伯菌 肝脓肿 高侵袭力肺炎克雷伯菌 定义 临床特征 

分 类 号：R446.5[医药卫生—诊断学]