男性生育力保存的研究进展  

Research progress of male fertility preservation

作　　者：陈其桂(综述) 檀大羡 刘刚(审校) CHEN Qigui;TAN Daxian;LIU Gang(Department of Andrology,Reproduction Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi 530029,China)

机构地区：[1]广西壮族自治区生殖医院男性科,广西南宁530029

出　　处：《现代医药卫生》2024年第23期4101-4105,4110,共6页Journal of Modern Medicine & Health

基　　金：南宁市青秀区科技计划项目(2020030)。

摘　　要：由于全球范围内不育症高发,精液质量持续下降,肿瘤发病率上升且日趋年轻化,非肿瘤人群需求增加,男性生育力保存近年来发展迅速,是目前研究的热点。男性生育力保存以预防未来生育风险为目的,既可应用于肿瘤患者,也可应用于其他疾病影响、职业暴露及晚婚晚育等非肿瘤人群。精子保存、睾丸组织和精原干细胞冻存是生育力保存的方法。但是,目前男性生育力保存面临着质控管理不规范、公众认知度不足及伦理学问题等诸多挑战。因此,该文对男性生育力保存的现状、方法及适应人群进行综述,并对相关问题加以思考及展望未来发展方向,以期为临床医生提供理论依据和进一步探索的新思路。Male fertility preservation has developed rapidly in recent years and has become a research hotspot due to the high incidence of infertility worldwide,the continuous decline in semen quality,the increasing incidence of cancer and the increasing demand for non-cancer population.The purpose of male fertility preservation is to prevent future fertility risks,which can be applied not only to tumor patients,but also to non-tumor populations affected by other diseases,occupational exposure,late marriage and late childbearing.Sperm preservation,testicular tissue and spermatogonial stem cell cryopreservation are the methods of fertility preservation.However,at present,the preservation of male fertility faces many challenges,such as non-standard quality control management,lack of public awareness and ethical issues and so on.Therefore,this paper reviews the current situation,methods and adaptive population of male fertility preservation,and thinks about related problems and looks forward to the future development direction,in order to provide theoretical basis and new ideas for clinical physicians to further explore.

关 键 词：男性生育力保存 肿瘤 非肿瘤 综述 

分 类 号：R698.2[医药卫生—泌尿科学]