基于35 Y-STR研究甘肃裕固族的父系多重起源  

Multiple ancestral components and complex origins of the Yugur people in Gansu province revealing by 35 Y-STR

作　　者：张咸鹏 于会新 张劼 贾欣怡 何宵飞 朱波峰 韦兰海 姚宏兵 Xianpeng Zhang;Huixin Yu;Jie Zhang;Xinyi Jia;Xiaofei He;Bofeng Zhu;Lanhai Wei;Hongbing Yao(School of Ethnology and Anthropology,Inner Mongolia Normal University,Hohhot 010000,China;Belt and Road Research Center for Forensic Molecular Anthropology,Gansu University of Political Science and Law,Lanzhou 730000,China;Institute of Evidence Law and Forensic Science,China University of Political Science and Law,Beijing 100000,China;Guangzhou Key Laboratory of Forensic Multi-Omics for Precision Identification,School of Forensic Medicine,Southern Medical University,Guangzhou 510000,China;MOE Key Laboratory of Contemporary Anthropology,School of Life Sciences,Fudan University,Shanghai 200000,China)

机构地区：[1]内蒙古师范大学民族学人类学学院,呼和浩特010000 [2]甘肃政法大学一带一路法医分子人类学研究中心,兰州730000 [3]中国政法大学证据科学研究院,北京100000 [4]南方医科大学法医学学院广州市法医多组学精准鉴定重点实验室,广州510000 [5]复旦大学生命科学学院现代人类学教育部重点实验室,上海200000

出　　处：《遗传》2024年第12期1042-1054,共13页Hereditas（Beijing)

基　　金：内蒙古自治区直属高校基本科研业务费项目(编号:2022JBBJ004);内蒙古师范大学研究生科研创新基金资助项目(编号:CXJJB23005);国家自然科学基金(编号:31760309);教育部人文社科规划基金(编号:18YJAZH116);甘肃省引导科技创新专项(编号:2018ZX03);兰州市人才创新创业项目(编号:2018-RC-113);甘肃省高校产业支撑计划项目(编号:2023CYZC-59)资助。

摘　　要：裕固族是甘肃省特有少数民族,具有人口少、多语并用和复杂族源等特征,是河西走廊人群的典型代表。关于裕固族的起源、迁徙及形成过程,学界尚存在许多有争议的内容。本研究将从分子人类学的视角,以裕固族的父系遗传特征为依据,结合民族学、历史学和语言学等学科相关内容,进一步研究裕固族的形成过程。本研究使用含35个Y-STR的高分辨率试剂盒对237例甘肃裕固族男性样本进行了检测,并使用Y-STR分析推定了Y-SNP单倍群。本文整合已发布文献中多个群体的父系遗传数据,组成16Y-STR数据集、25Y-STR数据集和单倍群频率数据集,使用Network网络图、主成分分析、多维尺度分析、系统发育树和遗传距离等分析方法系统地分析了裕固族人群的父系遗传特征及其与周边人群的遗传关系。结果显示,裕固族的父系遗传组成表现出东西欧亚人群混合的特征,西欧亚谱系占13%;其与地理位置相近的汉族、藏族和蒙古族等人群表现出更近的遗传关系,而与维吾尔族等突厥语人群间的遗传距离较大;裕固族的遗传结构是演化过程中多族系融合的结果,与突厥语人群共享的Q1b1a3-L330和R1a1a-M17、与蒙古语人群共享的C2a1a1-F1756、C2a1a3-M504、C2a1a3a-F3796、C2a1a2-M48和C2b1a1a1a-M407、与藏族人群共享的D1a1a-M15和D1a1b1-P47,以及与汉族人群共享的多个支系是裕固族主要的父系类型。本文以更清晰的图景支持历史学、民族学和语言学所记述的裕固族形成过程及群体特征,为未来更细化的群体遗传学和法医遗传学研究打下基础。The Yugur people represent one of the ethnic groups residing within the Hexi Corridor,distinguishable by their small population size,linguistic diversity,intricate ancestral components,serving as a quintessential exemplar of the populations inhabiting this corridor.There are still many controversial issues in the academic community regarding the origin,migration,and formation process of the Yugur.In this study,we explored the formation process of the Yugur from the perspective of molecular anthropology,based on the paternal genetic characteristics of the Yugur people.And the study will synthesize multiple disciplines,encompassing ethnology,history and linguistics,in order to offer a thorough analysis.Within this research endeavor,a high-resolution kit comprising 35 Y-STRs was employed to examine 237 male specimens from the Yugur people in Gansu province.Y-SNP haplogroups were deduced through the utilization of Y-STR data.The paternal genetic data from diverse populations documented in published literature were merged to construct a 16 Y-STR dataset,a 25 Y-STR dataset,and a dataset detailing haplogroup frequencies.In this study,we employed haplotype network analysis,principal component analysis,multidimensional scaling analysis,phylogenetic tree construction,and genetic distance calculations to delve into the genetic structure,haplotype distribution,and genetic relationship with neighboring populations of the Yugur people.The findings of this study reveal that the Yugur people are a blend of ancestral lineages from both Eastern and Western Eurasian origins,with approximately 13%of their genetic component traced back to Western Eurasian populations.The Yugur people in Gansu province exhibits a more intimate genetic relationship with the Han,Tibetan,and Mongolian populations inhabiting nearby regions,while showing distinct genetic differences with Turkic-speaking groups like the Uyghur.Based on the merged data,we identified Q1b1a3-L330 and R1a1a-M17 shared with Turkic-speaking people,C2a1a1-F1756,C2a1a3-M504,C2a1a3a

关 键 词：Y-STR 裕固族 父系遗传结构 多重起源 

分 类 号：Q987[生物学—遗传学]