Balancing Microbiome as a Promising Approach for Scalp Care——the Basic Concept and an in Vitro Proof  

作　　者：Wang Fangfang Lin Xianting Yang Jianzhong 

机构地区：[1]Beauty Hi-tech Innovation Co.,Ltd.,Japan [2]O and R Co.,Ltd.,Japan

出　　处：《China Detergent & Cosmetics》2024年第4期64-69,共6页日用化学品科学（英文版）

摘　　要：The human scalp harbors a diverse range of microbiome,much like other skin surfaces,where both beneficial and harmful microorganisms coexist.This study explores the possibility of balancing key scalp microorganisms,particularly Staphylococcus epidermidis,Staphylococcus aureus and Malassezia species.While Staphylococcus epidermidis plays a beneficial role in maintaining scalp health by producing antimicrobial proteins and supporting the skin barrier,Staphylococcus aureus is identified as a pathogen linked to skin infections and dandruff formation.Malassezia fungi degrade triglycerides in sebum into unsaturated fatty acids,exacerbating scalp conditions like dandruff.In order to promote the beneficial microbe while inhibit the harmful ones,we investigated the combination of 1.0 mM pyrrolidone carboxylate-zinc(PCA-Zn),0.2%malt oligosaccharides(MT:corn-derived oligosaccharide mainly containing maltotetraose)and 0.05 mM Hinokitiol on its microbial activity,which significantly enhanced the growth of Staphylococcus epidermidis while inhibiting both Staphylococcus aureus and Malassezia,offering insights into promising strategies for scalp care.

关 键 词：microbial barrier scalp microbiome microecological balance DANDRUFF PATHOGEN HINOKITIOL 

分 类 号：TQ658.3[化学工程—精细化工]