The First Case of Serogroup Y Neisseria meningitidis and An Expanded Investigation of Healthy Carriers—Shijiazhuang City,Hebei Province,China,2023  

作　　者：Yumei Guo Yuwen Cao Baohua He Xinyan Dong Meng Bi Xiaoli Wang Teng Gao Xingle Liu Ke Wang Yuhao Wang Hong Zhang Yinqi Sun Weili Gao Yulan Zhang Zhaoyi Jia 

机构地区：[1]Shijiazhuang Center for Disease Control and Prevention,Hebei Key Laboratory of Intractable Pathogens,Shijiazhuang City,Hebei Province,China [2]Hebei Provincial Center for Disease Control and Prevention Bacterial Disease Prevention and Disinfection Institute,Hebei Key Laboratory of Pathogens and Epidemiology of Infectious Diseases,Shijiazhuang City,Hebei Province,China [3]Chinese Center for Disease Control and Prevention,Beijing,China

出　　处：《China CDC weekly》2024年第47期1242-1247,I0009-I0011,共9页中国疾病预防控制中心周报（英文）

基　　金：Supported by Hebei Provincial Health Commission Project(No.20200683);Hebei Provincial Science and Technology Plan Project(No.223777116D);Hebei Province Medical Applicable Technology Tracking Project(No.GX2025169).

摘　　要：What is already known about this topic?Neisseria meningitidis(Nm)is a bacterial pathogen that causes meningococcal disease.Serogroups A,B,C,W,X,and Y account for the vast majority of cases.However,invasive meningococcal disease(IMD)caused by NmY is rare in China and has been reported only in Tianjin,Guangdong,Shanghai,and Hunan provinces and cities.What is added by this report?This article reports the first case of NmY:cc23 meningococcal disease in Hebei Province,confirmed by metagenomic sequencing.We also present the results of expanded surveillance in the healthy population associated with the case.What are the implications for public health practice?NmY has caused multiple case reports across China,especially in southern cities.The first report of a serogroup Y case in Hebei Province,and the carriage rate in the healthy population,reminds us to increase public health attention on Nm.The results of this study suggest that surveillance of the Nm carriage rate among healthy carriers and serogroup changes in Nm should be strengthened.

关 键 词：Hebei STRENGTHENED expanded 

分 类 号：R512.3[医药卫生—内科学]