基于CiteSpace和VOSviewer的药食同源中药抗衰老研究进展可视化分析  

Visual analysis of research progress on anti-aging effect of traditional Chinese medicine with medicine food homology based on CiteSpace and VOSviewer

作　　者：曾凡沐辰 叶贤龙 于伟 熊凤敏 陈英莉 杨慧林[2] 姜旋 ZENG Fanmuchen;YE Xianlong;YU Wei;XIONG Fengmin;CHEN Yingli;YANG Huilin;JIANG Xuan(Ganjiang Chinese Medicine Innovation Center,Nanchang 330000,China;Key Laboratory of Protection and Utilization of Subtropical Plant Resources of Jiangxi Province,College of Life Sciences,Jiangxi Normal University,Nanchang 330022,China;Dalian Institute of Chemical Physics,Chinese Academy of Sciences,Dalian 116023,China)

机构地区：[1]赣江中药创新中心,江西南昌330000 [2]江西师范大学生命科学学院,江西省亚热带植物资源保护与利用重点实验室,江西南昌330022 [3]中国科学院大连化学物理研究所,辽宁大连116023

出　　处：《中草药》2024年第22期7786-7798,共13页Chinese Traditional and Herbal Drugs

基　　金：赣江中药创新中心自主部署项目(CMSC32309);江西省双千项目(jxsq2020101090)。

摘　　要：目的 对药食同源中药抗衰老研究现状和热点进行可视化分析,为今后的深入研究和临床应用提供参考。方法 研究数据来源于中国知网(CNKI)和Web of Science数据库,对数据库自建库起至2024年的文献进行筛选。利用CiteSpace和VOSviewer软件对文献的关键词、作者、机构进行可视化分析。结果 纳入中文文献588篇,英文文献277篇。药食同源中药抗衰老领域发文量呈波动上升的趋势,中英文文献各有60位和59位作者发文量突出,中文文献以吉林农业大学等机构为中心形成紧密合作网络,英文文献中Chinese Academy of Sciences(中国科学院)与Consejo Nacional de Investigaciones Cientificas y Tecnicas(CONICET)等机构发文量位于前列。发文期刊方面,食品工业科技和Journal of Ethnobiology and Ethnomedicine分别在中英文领域发文量领先。中文文献中抗氧化、药理、化学成分和多糖等关键词频繁出现,英文文献则聚焦于药用植物和氧化应激等。聚类和突现分析显示药食同源、桑叶、肠道菌群等为研究热点,英文文献突出抗氧化活性和食物活性成分的作用。共现密度视图显示了抗氧化、多糖、抗衰老等关键词的研究热度。结论 目前药食同源中药抗衰老的研究热点主要集中在分离纯化、药理作用、营养成分、抗氧化、多糖等方面,尚存在团队间缺乏大规模合作、研究深度不够等不足。未来针对具有抗衰老的药食同源中药研究将聚焦于代谢组学、转录组学、肠道菌群等多方面的相互作用。Objective To provide reference for future in-depth research and clinical application by visualizing and analyzing the current status and hot direction of the research on anti-aging of medicine and food homologous traditional Chinese medicine.Methods Data were retrieved from the China National Knowledge Infrastructure(CNKI)and Web of Science databases,covering publications from their inception to 2024.Visualization and analysis of keywords,authors,and institutions in the literature were conducted using CiteSpace and VOSviewer softwares.Results A total of 588 Chinese and 277 English literature were included.The number of publications in the field of anti-aging effects of food and medicinal homologous traditional Chinese medicine has shown a fluctuating upward trend,with 60 and 59 authors in Chinese and English literatures respectively.Chinese literature forms a tightly-knit cooperative network centered around institutions such as Jilin Agricultural University,In the English literature,the number of papers published by institutions such as the Chinese Academy of Sciences and CONICET are at the forefront.In terms of journals,Food Industry Science and Technology and Journal of Ethnobiology and Ethnomedicine lead in the number of articles published in Chinese and English,respectively.Keywords such as antioxidant,pharmacology,chemical composition and polysaccharides frequently appear in Chinese literature,while English literature focuses on medicinal plants and oxidative stress.Cluster and emergence analysis showed that medicine and food homology,mulberry leaves,gut microbiota,etc.were research hotspots,and English literature highlighted the role of antioxidant activity and active ingredients in food.The co-occurrence density view showed the research popularity of keywords such as antioxidant,polysaccharide,and anti-aging.Conclusion Currently,the research hotspots on the anti-aging effects of food and medicinal homologous traditional Chinese medicine mainly focus on isolation and purification,pharmacological effects,nut

关 键 词：药食同源 抗衰老 CITESPACE VOSviewer 可视化分析 抗氧化 多糖 

分 类 号：G350[文化科学—情报学] R285[医药卫生—中药学]