Interferometers Utilizing Reversible X-ray-induced Chemical Changes in Poly(N-isopropylacrylamide)Microgels  

作　　者：Ya-Jie Wang Ping Zhang Michael J Serpe Hong Chen Liang Hu 

机构地区：[1]State Key Laboratory of Radiation Medicine and Protection,Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions,and School for Radiological and Interdisciplinary Sciences(RAD-X),Soochow University,Suzhou 215123,China [2]State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials,College of Chemistry,Chemical Engineering and Materials Science,SoochowUniversity,Suzhou 215123,China [3]Department of Chemistry,University of Alberta,Edmonton,AB,T6G 2G2,Canada

出　　处：《Chinese Journal of Polymer Science》2024年第12期1915-1924,I0008,共11页高分子科学（英文版）

基　　金：supported by Natural Science Foundation of Jiangsu Province(No.BK20221359);Interdisciplinary Basic Frontier Innovation Program of Suzhou Medical College of Soochow University,State Key Laboratory of Radiation Medicine and Protection(No.GZC00501);the National Natural Science Foundation of China(No.51873137);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).

摘　　要：Photonic materials,which react to light,have garnered interest due to their capability to exhibit adjustable structural colors.Typically,light targets the UV,visible,or near-IR spectrums.In this study,microgel-based photonic materials that are capable of reversibly responding to Xrays have been engineered.To accomplish this,azobenzene(Azo)-containing poly(N-isopropylacrylamide)(pNiPAm)-based microgels are synthesized.Subsequently,ZnS scintillator and Cr/Au are applied on each side of the poly(methyl methacrylate(PMMA)substrate.Subsequently,the Azo MG monolayer is deposited onto the Au surface,followed by the deposition of an additional layer of Cr/Au.This process generates ZnS/PMMA/Cr/Au/Azo MG/Cr/Au or ZnS/Au-Azo MG-Au structure.Functioning as a typical interferometer,ZnS/Au-Azo MG-Au demonstrates tunable colors based on the separation distance between the two Au layers.The ZnS scintillator can absorb and convert X-rays into Uv light,initiating the transition of the Azo groups from a trans to a cis state.Consequently,this transition causes the Azo MG to swell.As Azo MG swells,the distance between the two Au layers increases,resulting in a red-shift of approximately 350 nm in the optical signal of the ZnS/Au-Azo MG-Au interferometer.Remarkably,this X-ray responsivity of the interferometer is reversible,as it returns to its initial state after being stored in the dark for 24 h.To demonstrate its capabilities,the ZnS/Au-Azo MG-Au interferometer successfully releases a drug when triggered by X-ray stimulation,thus validating its potential.The microgel-based interferometers hold significant promise for applications in chemoradiotherapy,radiobiology,and actuators in space.

关 键 词：N-ISOPROPYLACRYLAMIDE Microgels INTERFEROMETERS X-rays SCINTILLATORS 

分 类 号：TH744.3[机械工程—光学工程] TQ427.26[机械工程—仪器科学与技术]