维生素A棕榈酸酯眼用凝胶联合地夸磷索钠滴眼液在白内障超声乳化术后干眼症的应用效果  

Effect of Vitamin A Palmitate Ophthalmic Gel Combined with Dexamethasone Sodium Eye Drops on Dry Eye after Phacoemulsification

作　　者：苏楠 蒋蕾 张婧妍 蔺波 杨侃 SU Nan;JIANG Lei;ZHANG Jingyan;LIN Bo;YANG Kan(Department of Ophthalmic,The First People's Hospital of Lanzhou,Lanzhou 730000,Gansu,China)

机构地区：[1]兰州市第一人民医院眼科,甘肃兰州730000

出　　处：《系统医学》2024年第22期53-55,59,共4页Systems Medicine

摘　　要：目的探讨白内障超声乳化术后干眼症患者应用维生素A棕榈酸酯眼用凝胶联合地夸磷索钠滴眼液的效果。方法非随机选取2022年1—12月兰州市第一人民医院204例白内障超声乳化术后干眼症患者,按治疗方法不同分为对照组(地夸磷索钠滴眼液)102例和观察组(维生素A棕榈酸酯眼用凝胶+地夸磷索钠滴眼液)102例。对比两组治疗后的临床疗效,治疗前后泪液炎性因子水平和视觉相关生存质量。结果观察组总疗效率为98.03%(100/102),高于对照组的90.20%(92/102),差异有统计学意义(χ^(2)=5.666,P<0.05);治疗4周后观察组炎症因子水平低于对照组,视觉相关生存质量评分高于对照组,差异有统计学意义(P均<0.05)。结论白内障超声乳化术后干眼患者联用维生素A棕榈酸酯眼用凝胶和地夸磷索钠滴眼液能够改善其泪液炎症因子水平,提高临床疗效和生活质量。Objective To investigate the effect of vitamin A palmitate ophthalmic gel combined with dexamethasone sodium eye drops on dry eye patients after phacoemulsification.Methods From January to December 2022,204 cases of dry eyes after phacoemulsification in Lanzhou First People's Hospital were non-randomly selected and divided into the control group(n=102,dexamethasone sodium eye drops)and the observation group(n=102,vitamin A palmitate eye gel+dexamethasone sodium eye drops)according to different treatment methods.Compare the clinical efficacy of two groups after treatment,as well as tear inflammatory factor levels before and after treatment and visual related quality of life.Results The total treatment efficiency of the observation group was 98.03%(100/102),which was higher than 90.20%(92/102)of the control group,and the difference was statistically significant(χ^(2)=5.666,P<0.05);After 4 weeks of treatment,the levels of inflammatory factors in the observation group were lower than those in the control group,and the visual related quality of life score were higher than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion After phacoemulsification,vitamin A palmitate eye gel combined with diquafosol eye drops can improve the level of tear inflammatory factors,improve clinical efficacy and quality of life.

关 键 词：维生素A棕酯眼用凝胶 地跨磷酸钠滴眼液 白内障超声乳化术 泪液炎症因子 

分 类 号：R59[医药卫生—内科学]